Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge
Here we report a rare case of diffuse leptomeningeal glioneuronal tumor (DLGNT) in a 35-year-old man, who was misdiagnosed twice as having tuberculosis meningitis and later racemose neurocysticercosis. His delayed diagnosis of DLGNT might be due to prevalence of tuberculosis in our country, similari...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-01-01
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| Series: | Indian Journal of Neurosurgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1730130 |
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| author | Mukesh Kumar Bhaskar Mukta Meel Kusum Mathur Arpita Jindal Mohit Khandelwal |
| author_facet | Mukesh Kumar Bhaskar Mukta Meel Kusum Mathur Arpita Jindal Mohit Khandelwal |
| author_sort | Mukesh Kumar Bhaskar |
| collection | DOAJ |
| description | Here we report a rare case of diffuse leptomeningeal glioneuronal tumor (DLGNT) in a 35-year-old man, who was misdiagnosed twice as having tuberculosis meningitis and later racemose neurocysticercosis. His delayed diagnosis of DLGNT might be due to prevalence of tuberculosis in our country, similarity in magnetic resonance imaging finding of prominent leptomeningeal enhancement in different cisterns of brain, and extreme rarity of DLGNT in the adults. So, it should be differentiated clinically and radiographically from granulomatous or infectious conditions. Hence, a timely histologic diagnosis through a leptomeningeal biopsy of the brain and spinal cord in case of unusual leptomeningeal enhancement with uncertain laboratory findings is essential because cytological examination of the cerebrospinal fluid in DLGNT is known to be negative. |
| format | Article |
| id | doaj-art-eecb64702ee640efbc9558ed53f9c66c |
| institution | DOAJ |
| issn | 2277-954X 2277-9167 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Neurosurgery |
| spelling | doaj-art-eecb64702ee640efbc9558ed53f9c66c2025-08-20T03:21:14ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672022-01-01110107607910.1055/s-0041-1730130Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic ChallengeMukesh Kumar Bhaskar0Mukta Meel1Kusum Mathur2Arpita Jindal3Mohit Khandelwal4Department of Neurosurgery, Swai Man Singh Medical College, Jaipur, Rajasthan, IndiaDepartment of Pathology, Swai Man Singh Medical College, Jaipur, Rajasthan, IndiaDepartment of Pathology, Swai Man Singh Medical College, Jaipur, Rajasthan, IndiaDepartment of Pathology, Swai Man Singh Medical College, Jaipur, Rajasthan, IndiaSuryam Diagnostic Centre, Swai Man Singh Medical College, Jaipur, Rajasthan, IndiaHere we report a rare case of diffuse leptomeningeal glioneuronal tumor (DLGNT) in a 35-year-old man, who was misdiagnosed twice as having tuberculosis meningitis and later racemose neurocysticercosis. His delayed diagnosis of DLGNT might be due to prevalence of tuberculosis in our country, similarity in magnetic resonance imaging finding of prominent leptomeningeal enhancement in different cisterns of brain, and extreme rarity of DLGNT in the adults. So, it should be differentiated clinically and radiographically from granulomatous or infectious conditions. Hence, a timely histologic diagnosis through a leptomeningeal biopsy of the brain and spinal cord in case of unusual leptomeningeal enhancement with uncertain laboratory findings is essential because cytological examination of the cerebrospinal fluid in DLGNT is known to be negative.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1730130adultdiffuse leptomeningeal glioneuronal tumorleptomeningeal biopsy |
| spellingShingle | Mukesh Kumar Bhaskar Mukta Meel Kusum Mathur Arpita Jindal Mohit Khandelwal Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge Indian Journal of Neurosurgery adult diffuse leptomeningeal glioneuronal tumor leptomeningeal biopsy |
| title | Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge |
| title_full | Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge |
| title_fullStr | Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge |
| title_full_unstemmed | Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge |
| title_short | Diffuse Leptomeningeal Glioneuronal Tumor in an Adult: A Diagnostic Challenge |
| title_sort | diffuse leptomeningeal glioneuronal tumor in an adult a diagnostic challenge |
| topic | adult diffuse leptomeningeal glioneuronal tumor leptomeningeal biopsy |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1730130 |
| work_keys_str_mv | AT mukeshkumarbhaskar diffuseleptomeningealglioneuronaltumorinanadultadiagnosticchallenge AT muktameel diffuseleptomeningealglioneuronaltumorinanadultadiagnosticchallenge AT kusummathur diffuseleptomeningealglioneuronaltumorinanadultadiagnosticchallenge AT arpitajindal diffuseleptomeningealglioneuronaltumorinanadultadiagnosticchallenge AT mohitkhandelwal diffuseleptomeningealglioneuronaltumorinanadultadiagnosticchallenge |