Genetic trends and common BRCA1/2 pathogenic sequence variants in black African and Indian breast cancer patients presenting at Inkosi Albert Luthuli Central Hospital, KwaZulu-Natal, South Africa

Background. Hereditary breast cancer is characterised by the presence of a pathogenic sequence variant passed from one generation to the next. These cancers are aggressive, develop early, and account for 5 - 10% of all breast cancer cases. In South Africa (SA), the common variants that predispo...

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Bibliographic Details
Main Authors: M Makhetha, C Aldous, N Chabilal
Format: Article
Language:English
Published: South African Medical Association 2024-05-01
Series:South African Medical Journal
Subjects:
Online Access:https://samajournals.co.za/index.php/samj/article/view/1094
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