Photo-mediated para-selective C(sp2)−H difluoroalkylations

Photo-mediated ruthenium-catalyzed para-C−H difluoroalkylation has been disclosed under extremely mild conditions. This photochemical ruthenium catalyst system is characterized by good functional group compatibility without additional photosensitizers at room temperature.

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Main Authors: Yi Luo, Lin Dong
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-02-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554923000996
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author Yi Luo
Lin Dong
author_facet Yi Luo
Lin Dong
author_sort Yi Luo
collection DOAJ
description Photo-mediated ruthenium-catalyzed para-C−H difluoroalkylation has been disclosed under extremely mild conditions. This photochemical ruthenium catalyst system is characterized by good functional group compatibility without additional photosensitizers at room temperature.
format Article
id doaj-art-eebd6b3247fd4b19867ebaa9a1b7b34e
institution DOAJ
issn 2666-5549
language English
publishDate 2025-02-01
publisher KeAi Communications Co. Ltd.
record_format Article
series Green Synthesis and Catalysis
spelling doaj-art-eebd6b3247fd4b19867ebaa9a1b7b34e2025-08-20T02:45:50ZengKeAi Communications Co. Ltd.Green Synthesis and Catalysis2666-55492025-02-0161919510.1016/j.gresc.2023.11.005Photo-mediated para-selective C(sp2)−H difluoroalkylationsYi Luo0Lin Dong1Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, ChinaCorresponding author.; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, ChinaPhoto-mediated ruthenium-catalyzed para-C−H difluoroalkylation has been disclosed under extremely mild conditions. This photochemical ruthenium catalyst system is characterized by good functional group compatibility without additional photosensitizers at room temperature.http://www.sciencedirect.com/science/article/pii/S2666554923000996Ruthenium catalysisPhotochemical systemC–H difluoroalkylationpara selectivity
spellingShingle Yi Luo
Lin Dong
Photo-mediated para-selective C(sp2)−H difluoroalkylations
Green Synthesis and Catalysis
Ruthenium catalysis
Photochemical system
C–H difluoroalkylation
para selectivity
title Photo-mediated para-selective C(sp2)−H difluoroalkylations
title_full Photo-mediated para-selective C(sp2)−H difluoroalkylations
title_fullStr Photo-mediated para-selective C(sp2)−H difluoroalkylations
title_full_unstemmed Photo-mediated para-selective C(sp2)−H difluoroalkylations
title_short Photo-mediated para-selective C(sp2)−H difluoroalkylations
title_sort photo mediated para selective c sp2 h difluoroalkylations
topic Ruthenium catalysis
Photochemical system
C–H difluoroalkylation
para selectivity
url http://www.sciencedirect.com/science/article/pii/S2666554923000996
work_keys_str_mv AT yiluo photomediatedparaselectivecsp2hdifluoroalkylations
AT lindong photomediatedparaselectivecsp2hdifluoroalkylations