Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria.
Antibiotic resistance is a continuously increasing concern for public healthcare. Understanding resistance mechanisms and their emergence is crucial for the development of new antibiotics and their effective use. The peptide antibiotic albicidin is such a promising candidate that, as a gyrase poison...
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| Main Authors: | Mareike Saathoff, Simone Kosol, Torsten Semmler, Karsten Tedin, Nicole Dimos, Johannes Kupke, Maria Seidel, Fereshteh Ghazisaeedi, Micela Condor Jonske, Silver A Wolf, Benno Kuropka, Wojciech Czyszczoń, Dmitry Ghilarov, Stefan Grätz, Jonathan G Heddle, Bernhard Loll, Roderich D Süssmuth, Marcus Fulde |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-08-01
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| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002186&type=printable |
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