Enhancing aptamer selection in alzheimer’s disease: integrating structure prediction and molecular dynamics simulations
Abstract Alzheimer’s disease is the most frequent neurodegenerative disease and the leading cause of dementia worldwide. With disease-modifying treatments highly requested, numerous aptamers have been experimentally selected, showing high affinity and specificity binding to the main drivers in the p...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-12186-1 |
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