Coordination acid-engineered Prussian Blue affects glycometabolic reprogramming in microglia for epileptic treatment

Coordination acid-engineered Prussian Blue affects glycometabolic reprogramming in microglia for epileptic treatment

Abstract Seizures induce significant immune and metabolic stress in microglia, but the interaction between these processes remains unclear. This study, utilizing single-nucleus RNA sequencing data from temporal lobe epilepsy (TLE) patients, reveals that reactive oxygen species (ROS) stabilize hypoxi...

Full description

Saved in:
Bibliographic Details
Main Authors: Yao Zhao, Feixiang Chen, Chen Chen, Yuling Yang, Luo Wang, Jiaqi Zhu, Xin Wang, Yanyan Liu, Jing Ding
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Nanobiotechnology
Subjects:
Temporal lobe epilepsy
Microglia
Metabolic reprogramming
Local pKa
Nanocatalyst
Online Access:https://doi.org/10.1186/s12951-025-03408-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items