Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study
Background Respiration is an intricate interaction between visceral and musculoskeletal structures. In cystic fibrosis (CF), the airways and lungs are subject to progressive obstruction and destruction. However, knowledge about the musculoskeletal aspects of respiratory function and symptoms is stil...
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| Format: | Article |
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Taylor & Francis Group
2024-12-01
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| Series: | European Clinical Respiratory Journal |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20018525.2024.2350206 |
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| author | Niklas Sinderholm Sposato Kristofer Bjerså Marita Gilljam Louise Lannefors Monika Fagevik Olsén |
| author_facet | Niklas Sinderholm Sposato Kristofer Bjerså Marita Gilljam Louise Lannefors Monika Fagevik Olsén |
| author_sort | Niklas Sinderholm Sposato |
| collection | DOAJ |
| description | Background Respiration is an intricate interaction between visceral and musculoskeletal structures. In cystic fibrosis (CF), the airways and lungs are subject to progressive obstruction and destruction. However, knowledge about the musculoskeletal aspects of respiratory function and symptoms is still limited in this patient group.Methods In a cross-sectional comparative study, 21 adults with CF enrolled at the Gothenburg CF Centre were matched with 42 healthy controls. The two groups were examined and compared in terms of thoracic mobility, respiratory muscle strength, lung function, and musculoskeletal pain in accordance with a predefined protocol.Results Significant differences were observed between the groups in the number of tender points, thoracic excursion, forced vital capacity (FVC), and forced expiratory volume (FEV). The CF group also demonstrated a tendency toward reduced function in other measurements, although these were not statistically significant.Conclusion This cross-sectional study revealed that people with CF have reduced thoracic mobility and an increased prevalence of muscular tender points, alongside decreased lung function, compared to healthy controls. These findings stress the need for greater emphasis on the often-overlooked musculoskeletal aspects of CF care, especially as people with CF are living longer and may require more musculoskeletal health support. |
| format | Article |
| id | doaj-art-eeb3bd6e0c3042e2aadc82179f38dd37 |
| institution | OA Journals |
| issn | 2001-8525 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Clinical Respiratory Journal |
| spelling | doaj-art-eeb3bd6e0c3042e2aadc82179f38dd372025-08-20T02:27:43ZengTaylor & Francis GroupEuropean Clinical Respiratory Journal2001-85252024-12-0111110.1080/20018525.2024.2350206Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative studyNiklas Sinderholm Sposato0Kristofer Bjerså1Marita Gilljam2Louise Lannefors3Monika Fagevik Olsén4Department of Health and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenDepartment of Respiratory Medicine, Sahlgrenska University Hospital, Gothenburg, SwedenDepartment of Health and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenDepartment of Health and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenBackground Respiration is an intricate interaction between visceral and musculoskeletal structures. In cystic fibrosis (CF), the airways and lungs are subject to progressive obstruction and destruction. However, knowledge about the musculoskeletal aspects of respiratory function and symptoms is still limited in this patient group.Methods In a cross-sectional comparative study, 21 adults with CF enrolled at the Gothenburg CF Centre were matched with 42 healthy controls. The two groups were examined and compared in terms of thoracic mobility, respiratory muscle strength, lung function, and musculoskeletal pain in accordance with a predefined protocol.Results Significant differences were observed between the groups in the number of tender points, thoracic excursion, forced vital capacity (FVC), and forced expiratory volume (FEV). The CF group also demonstrated a tendency toward reduced function in other measurements, although these were not statistically significant.Conclusion This cross-sectional study revealed that people with CF have reduced thoracic mobility and an increased prevalence of muscular tender points, alongside decreased lung function, compared to healthy controls. These findings stress the need for greater emphasis on the often-overlooked musculoskeletal aspects of CF care, especially as people with CF are living longer and may require more musculoskeletal health support.https://www.tandfonline.com/doi/10.1080/20018525.2024.2350206Cystic fibrosismuscle strengthrespirationmusculoskeletal painthoracic mobility |
| spellingShingle | Niklas Sinderholm Sposato Kristofer Bjerså Marita Gilljam Louise Lannefors Monika Fagevik Olsén Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study European Clinical Respiratory Journal Cystic fibrosis muscle strength respiration musculoskeletal pain thoracic mobility |
| title | Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study |
| title_full | Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study |
| title_fullStr | Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study |
| title_full_unstemmed | Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study |
| title_short | Musculoskeletal aspects of respiratory function in cystic fibrosis: a cross-sectional comparative study |
| title_sort | musculoskeletal aspects of respiratory function in cystic fibrosis a cross sectional comparative study |
| topic | Cystic fibrosis muscle strength respiration musculoskeletal pain thoracic mobility |
| url | https://www.tandfonline.com/doi/10.1080/20018525.2024.2350206 |
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