ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI)
Abstract: In May 2024, the Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute (NHLBI) hosted a hybrid workshop on “Extracorporeal membrane oxygenation (ECMO)-induced coagulopathy: strategic initiatives for research and clinical practice.” The event brought toge...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | Blood Vessels, Thrombosis & Hemostasis |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S295032722500021X |
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| author | Jerrold H. Levy Peta M. A. Alexander Alisa S. Wolberg Owen J. T. McCarty Anthony E. Pusateri Raquel R. Bartz Wolfgang Bergmeier Mitchell J. Cohen Jean M. Connors James H. Morrissey Matthew D. Neal Elisabeth T. Tracy Keith McCrae Bruce A. Sullenger |
| author_facet | Jerrold H. Levy Peta M. A. Alexander Alisa S. Wolberg Owen J. T. McCarty Anthony E. Pusateri Raquel R. Bartz Wolfgang Bergmeier Mitchell J. Cohen Jean M. Connors James H. Morrissey Matthew D. Neal Elisabeth T. Tracy Keith McCrae Bruce A. Sullenger |
| author_sort | Jerrold H. Levy |
| collection | DOAJ |
| description | Abstract: In May 2024, the Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute (NHLBI) hosted a hybrid workshop on “Extracorporeal membrane oxygenation (ECMO)-induced coagulopathy: strategic initiatives for research and clinical practice.” The event brought together clinicians, scientists, bioengineers, and policymakers to address the challenges of ECMO-associated coagulopathy and explore novel therapeutic approaches. Through expert presentations and collaborative discussions, the workshop focused on innovative anticoagulation strategies, precision medicine, and advanced diagnostics to enhance patient care. The discussions also identified critical research gaps and opportunities for future interdisciplinary collaboration. This summary reviews the current state of knowledge and outlines future research directions for improving ECMO-induced coagulopathy management. |
| format | Article |
| id | doaj-art-eeae38a3316142d58d6372e2bee2caa3 |
| institution | Kabale University |
| issn | 2950-3272 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Blood Vessels, Thrombosis & Hemostasis |
| spelling | doaj-art-eeae38a3316142d58d6372e2bee2caa32025-08-20T03:53:42ZengElsevierBlood Vessels, Thrombosis & Hemostasis2950-32722025-05-012210006410.1016/j.bvth.2025.100064ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI)Jerrold H. Levy0Peta M. A. Alexander1Alisa S. Wolberg2Owen J. T. McCarty3Anthony E. Pusateri4Raquel R. Bartz5Wolfgang Bergmeier6Mitchell J. Cohen7Jean M. Connors8James H. Morrissey9Matthew D. Neal10Elisabeth T. Tracy11Keith McCrae12Bruce A. Sullenger13Department of Anesthesiology, Critical Care, and Surgery (Cardiothoracic), Duke University School of Medicine, Durham, NC; Correspondence: Jerrold H. Levy, Duke University Medical Center, 2301 Erwin Rd, 5691H HAFS, Box 3094, Durham, NC 27710;Department of Cardiology, Boston Children’s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MADepartment of Pathology and Laboratory Medicine and University of North Carolina Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NCDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, ORNaval Medical Research Unit San Antonio, Joint Base San Antonio-Fort Sam Houston, Houston, TX; Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MDDepartment of Anesthesia, Wake Forest School of Medicine, Winston Salem, NCDepartment of Biochemistry and Biophysics and UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NCDepartment of Surgery, University of Colorado School of Medicine, Aurora, COHematology Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MADepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MIDepartment of Surgery, Trauma and Transfusion Medicine Research Center, University of Pittsburgh, Pittsburgh, PADepartment of Surgery, UNC Children’s, University of North Carolina School of Medicine, Chapel Hill, NCBenign Hematology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; Department of Vascular Medicine, Miller Family Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic Lerner College of Medicine, Cleveland, OHDepartment of Surgery, Duke University School of Medicine, Durham, NCAbstract: In May 2024, the Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute (NHLBI) hosted a hybrid workshop on “Extracorporeal membrane oxygenation (ECMO)-induced coagulopathy: strategic initiatives for research and clinical practice.” The event brought together clinicians, scientists, bioengineers, and policymakers to address the challenges of ECMO-associated coagulopathy and explore novel therapeutic approaches. Through expert presentations and collaborative discussions, the workshop focused on innovative anticoagulation strategies, precision medicine, and advanced diagnostics to enhance patient care. The discussions also identified critical research gaps and opportunities for future interdisciplinary collaboration. This summary reviews the current state of knowledge and outlines future research directions for improving ECMO-induced coagulopathy management.http://www.sciencedirect.com/science/article/pii/S295032722500021X |
| spellingShingle | Jerrold H. Levy Peta M. A. Alexander Alisa S. Wolberg Owen J. T. McCarty Anthony E. Pusateri Raquel R. Bartz Wolfgang Bergmeier Mitchell J. Cohen Jean M. Connors James H. Morrissey Matthew D. Neal Elisabeth T. Tracy Keith McCrae Bruce A. Sullenger ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI) Blood Vessels, Thrombosis & Hemostasis |
| title | ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI) |
| title_full | ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI) |
| title_fullStr | ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI) |
| title_full_unstemmed | ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI) |
| title_short | ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI) |
| title_sort | ecmo induced coagulopathy strategic initiatives for research and clinical practice a workshop report of the nhlbi |
| url | http://www.sciencedirect.com/science/article/pii/S295032722500021X |
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