The Effect of Anti-Inflammatory Dimethylmalonic Acid on the Neurobehavioral Phenotype of a Neonatal ASD Model Induced by Antiepileptic Valproic Acid

The Effect of Anti-Inflammatory Dimethylmalonic Acid on the Neurobehavioral Phenotype of a Neonatal ASD Model Induced by Antiepileptic Valproic Acid

<b>Background</b>: Valproic acid (VPA) is a medication used to treat epilepsy, bipolar disorder, and migraine. If taken during pregnancy, it can cause neural tube defects (NTDs) and leads to offspring ASD behavioral phenotype. It has recently been found that early postnatal VPA exposure...

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Bibliographic Details
Main Authors: Xiuwen Zhou, Xiaowen Xu, Lili Li, Yiming Jin, Qing Wang, Xinxin Wang, Meifang Jin, Hong Ni
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
dimethylmalonic acid
valproic acid
autism spectrum disorder
neonate
neurobehavior
Online Access:https://www.mdpi.com/2227-9059/13/7/1765
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