Subacute Thyroiditis: Clinical Presentation and Long Term Outcome

Few studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to review the demographic, anthropometric, clinical presentation, laboratory results, treatment, and disease outcome in Riyadh...

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Main Authors: Assim A. Alfadda, Reem M. Sallam, Ghadi E. Elawad, Hisham AlDhukair, Mossaed M. Alyahya
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/794943
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author Assim A. Alfadda
Reem M. Sallam
Ghadi E. Elawad
Hisham AlDhukair
Mossaed M. Alyahya
author_facet Assim A. Alfadda
Reem M. Sallam
Ghadi E. Elawad
Hisham AlDhukair
Mossaed M. Alyahya
author_sort Assim A. Alfadda
collection DOAJ
description Few studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to review the demographic, anthropometric, clinical presentation, laboratory results, treatment, and disease outcome in Riyadh region and to compare those with results from different regions of the Kingdom and different parts of the world. We reviewed the medical files of patients who underwent thyroid uptake scan during an 8-year period in King Khalid University Hospital. Only 25 patients had confirmed diagnosis of thyroiditis. Age and gender distribution were similar to other studies. Most patients presented with palpitation, goiter, and weight change. Elevated thyroid hormones, suppressed thyroid-stimulating hormone, and elevated ESR were reported. Among those, 7 cases of SAT were recorded. β-Blockers were prescribed to 57% and nonsteroidal anti-inflammatory drugs to 29% of SAT. Long follow-up demonstrated that 85.7% of SAT cases recovered, while 14.3% developed permanent hypothyroidism. In conclusion, SAT is uncommon in the central region of SA. Compared to the western region, corticosteroid is not commonly prescribed, and permanent hypothyroidism is not uncommon. A nation-wide epidemiological study to explain these interprovincial differences is warranted.
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institution Kabale University
issn 1687-8337
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language English
publishDate 2014-01-01
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series International Journal of Endocrinology
spelling doaj-art-eea7119f6cc64e7daf1f98983ba5bb0c2025-02-03T06:13:22ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/794943794943Subacute Thyroiditis: Clinical Presentation and Long Term OutcomeAssim A. Alfadda0Reem M. Sallam1Ghadi E. Elawad2Hisham AlDhukair3Mossaed M. Alyahya4Department of Medicine, College of Medicine, King Saud University, P.O. Box 2925 (38), Riyadh 11461, Saudi ArabiaClinical Chemistry Unit, Department of Pathology, College of Medicine, King Saud University, P.O. Box 2925 (30), Riyadh 11461, Saudi ArabiaDepartment of Medicine, College of Medicine, King Saud University, P.O. Box 2925 (38), Riyadh 11461, Saudi ArabiaNational Neuroscience Institute, King Fahad Medical City, Riyadh 11525, Saudi ArabiaNeurology Department, King Faisal Specialist Hospital & Research Center, Riyadh 11211, Saudi ArabiaFew studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to review the demographic, anthropometric, clinical presentation, laboratory results, treatment, and disease outcome in Riyadh region and to compare those with results from different regions of the Kingdom and different parts of the world. We reviewed the medical files of patients who underwent thyroid uptake scan during an 8-year period in King Khalid University Hospital. Only 25 patients had confirmed diagnosis of thyroiditis. Age and gender distribution were similar to other studies. Most patients presented with palpitation, goiter, and weight change. Elevated thyroid hormones, suppressed thyroid-stimulating hormone, and elevated ESR were reported. Among those, 7 cases of SAT were recorded. β-Blockers were prescribed to 57% and nonsteroidal anti-inflammatory drugs to 29% of SAT. Long follow-up demonstrated that 85.7% of SAT cases recovered, while 14.3% developed permanent hypothyroidism. In conclusion, SAT is uncommon in the central region of SA. Compared to the western region, corticosteroid is not commonly prescribed, and permanent hypothyroidism is not uncommon. A nation-wide epidemiological study to explain these interprovincial differences is warranted.http://dx.doi.org/10.1155/2014/794943
spellingShingle Assim A. Alfadda
Reem M. Sallam
Ghadi E. Elawad
Hisham AlDhukair
Mossaed M. Alyahya
Subacute Thyroiditis: Clinical Presentation and Long Term Outcome
International Journal of Endocrinology
title Subacute Thyroiditis: Clinical Presentation and Long Term Outcome
title_full Subacute Thyroiditis: Clinical Presentation and Long Term Outcome
title_fullStr Subacute Thyroiditis: Clinical Presentation and Long Term Outcome
title_full_unstemmed Subacute Thyroiditis: Clinical Presentation and Long Term Outcome
title_short Subacute Thyroiditis: Clinical Presentation and Long Term Outcome
title_sort subacute thyroiditis clinical presentation and long term outcome
url http://dx.doi.org/10.1155/2014/794943
work_keys_str_mv AT assimaalfadda subacutethyroiditisclinicalpresentationandlongtermoutcome
AT reemmsallam subacutethyroiditisclinicalpresentationandlongtermoutcome
AT ghadieelawad subacutethyroiditisclinicalpresentationandlongtermoutcome
AT hishamaldhukair subacutethyroiditisclinicalpresentationandlongtermoutcome
AT mossaedmalyahya subacutethyroiditisclinicalpresentationandlongtermoutcome