Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant
Background and Objectives: Senecio vulgaris L., a member of the Asteraceae family, has been widely employed in traditional Iranian herbal practices for centuries. This research seeks to analyze and compare the essential oil compositions and antibacterial characteristics of two distinct populations...
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| Language: | English |
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Tehran University of Medical Sciences
2025-02-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/5002 |
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| author | Fatemeh Hajmoradi Hamed Fathi Foozieh Moghadami |
| author_facet | Fatemeh Hajmoradi Hamed Fathi Foozieh Moghadami |
| author_sort | Fatemeh Hajmoradi |
| collection | DOAJ |
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Background and Objectives: Senecio vulgaris L., a member of the Asteraceae family, has been widely employed in traditional Iranian herbal practices for centuries. This research seeks to analyze and compare the essential oil compositions and antibacterial characteristics of two distinct populations of S. vulgaris.
Materials and Methods: Essential oils were obtained from the above-ground parts of these populations through hydrodistillation, and their chemical constituents were examined using gas chromatography-mass spectrometry. The antibacterial effectiveness of the essential oils against both Gram-positive and Gram-negative bacteria was evaluated employing the agar well diffusion technique.
Results: Monoterpene hydrocarbons were found to be dominated in both populations, with Humulene epoxide II being the primary constituent, constituting 17.87% in the first population and 21.55% in the second one. The agar-well diffusion method revealed significant antibacterial effects of the S. vulgaris essential oils. The findings indicated that the essential oil displayed heightened activity against Escherichia coli in both populations. Furthermore, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests indicated that Pseudomonas aeruginosa with concentrations of 400 µg/mL for both tests, was the most susceptible bacteria, while Streptococcus pyogenes with MIC = 800 and MBC>800 µg/mL was the most resistant in both populations of S. vulgaris.
Conclusion: This research highlights the significance of S. vulgaris as a valuable reservoir of monoterpene-rich oil exhibiting robust antibacterial characteristics, suggesting its potential use in the development of novel and naturally derived therapeutics for bacterial diseases.
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| format | Article |
| id | doaj-art-ee9ff6efbdfc4aaf8d8effd1c0f49e6a |
| institution | Kabale University |
| issn | 2008-3289 2008-4447 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj-art-ee9ff6efbdfc4aaf8d8effd1c0f49e6a2025-02-09T09:01:21ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472025-02-01171Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plantFatemeh Hajmoradi0Hamed Fathi1Foozieh Moghadami2Department of Biology, Faculty of Science, Payame Noor University, Tehran, IranDepartment of Biology, Faculty of Science, Payame Noor University, Tehran, Iran; Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, IranDepartment of Biology, Faculty of Science, Payame Noor University, Tehran, Iran Background and Objectives: Senecio vulgaris L., a member of the Asteraceae family, has been widely employed in traditional Iranian herbal practices for centuries. This research seeks to analyze and compare the essential oil compositions and antibacterial characteristics of two distinct populations of S. vulgaris. Materials and Methods: Essential oils were obtained from the above-ground parts of these populations through hydrodistillation, and their chemical constituents were examined using gas chromatography-mass spectrometry. The antibacterial effectiveness of the essential oils against both Gram-positive and Gram-negative bacteria was evaluated employing the agar well diffusion technique. Results: Monoterpene hydrocarbons were found to be dominated in both populations, with Humulene epoxide II being the primary constituent, constituting 17.87% in the first population and 21.55% in the second one. The agar-well diffusion method revealed significant antibacterial effects of the S. vulgaris essential oils. The findings indicated that the essential oil displayed heightened activity against Escherichia coli in both populations. Furthermore, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests indicated that Pseudomonas aeruginosa with concentrations of 400 µg/mL for both tests, was the most susceptible bacteria, while Streptococcus pyogenes with MIC = 800 and MBC>800 µg/mL was the most resistant in both populations of S. vulgaris. Conclusion: This research highlights the significance of S. vulgaris as a valuable reservoir of monoterpene-rich oil exhibiting robust antibacterial characteristics, suggesting its potential use in the development of novel and naturally derived therapeutics for bacterial diseases. https://ijm.tums.ac.ir/index.php/ijm/article/view/5002Gas chromatography-mass spectrometry;Herbal medicine;Humulene epoxide;Microbial sensitivity tests;Senecio vulgaris |
| spellingShingle | Fatemeh Hajmoradi Hamed Fathi Foozieh Moghadami Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant Iranian Journal of Microbiology Gas chromatography-mass spectrometry; Herbal medicine; Humulene epoxide; Microbial sensitivity tests; Senecio vulgaris |
| title | Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant |
| title_full | Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant |
| title_fullStr | Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant |
| title_full_unstemmed | Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant |
| title_short | Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant |
| title_sort | phytochemical components and antibacterial activity of two populations of senecio vulgaris l essential oils as traditional medicine plant |
| topic | Gas chromatography-mass spectrometry; Herbal medicine; Humulene epoxide; Microbial sensitivity tests; Senecio vulgaris |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/5002 |
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