Hodgkin's Disease in Patients with HIV Infection
Hodgkin lymphoma (HL) represents one of the most common non-AIDS-defining cancers with an increasing incidence overtime. Clinically, patients present advanced stages of disease with extranodal involvement in the majority of cases. In the last years, significant improvements in the treatment of patie...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2011/402682 |
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| _version_ | 1841524425850093568 |
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| author | Michele Spina Antonino Carbone Annunziata Gloghini Diego Serraino Massimiliano Berretta Umberto Tirelli |
| author_facet | Michele Spina Antonino Carbone Annunziata Gloghini Diego Serraino Massimiliano Berretta Umberto Tirelli |
| author_sort | Michele Spina |
| collection | DOAJ |
| description | Hodgkin lymphoma (HL) represents one of the most common non-AIDS-defining cancers with an increasing incidence overtime. Clinically, patients present advanced stages of disease with extranodal involvement in the majority of cases. In the last years, significant improvements in the treatment of patients with HL and HIV infection have been achieved. In the lack of randomized trials, several phase II studies have showed that in the era of highly active antiretroviral therapy (HAART) the same regimens employed in HIV-negative patients with HL can be used in HIV setting with similar results. Moreover, in the last years the feasibility of high dose chemotherapy and peripheral stem cell rescue has allowed to save those patients who failed the upfront treatment.
Finally, in the near future, a better integration of diagnostic tools (including PET scan), chemotherapy (including new drugs), radiotherapy, HAART, and supportive care will significantly improve the outcome of these patients. |
| format | Article |
| id | doaj-art-ee9e9607b61145a9a2f2837381876ab6 |
| institution | Kabale University |
| issn | 1687-9104 1687-9112 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Hematology |
| spelling | doaj-art-ee9e9607b61145a9a2f2837381876ab62025-02-03T05:53:15ZengWileyAdvances in Hematology1687-91041687-91122011-01-01201110.1155/2011/402682402682Hodgkin's Disease in Patients with HIV InfectionMichele Spina0Antonino Carbone1Annunziata Gloghini2Diego Serraino3Massimiliano Berretta4Umberto Tirelli5Division of Medical Oncology, National Cancer Institute, via Franco Gallini 2, 33081 Aviano (PN), ItalyDivision of Pathology, National Cancer Institute, via Franco Gallini 2, 33081 Aviano (PN), ItalyDepartment of Pathology, and Laboratory Medicine, Fondazione IRCCS, National Cancer Institute, via Giacomo Venezian 1, 20133 Milan, ItalyUnit of Epidemiology and Biostatistics, National Cancer Institute, via Franco Gallini 2, 33081 Aviano (PN), ItalyDivision of Medical Oncology, National Cancer Institute, via Franco Gallini 2, 33081 Aviano (PN), ItalyDivision of Medical Oncology, National Cancer Institute, via Franco Gallini 2, 33081 Aviano (PN), ItalyHodgkin lymphoma (HL) represents one of the most common non-AIDS-defining cancers with an increasing incidence overtime. Clinically, patients present advanced stages of disease with extranodal involvement in the majority of cases. In the last years, significant improvements in the treatment of patients with HL and HIV infection have been achieved. In the lack of randomized trials, several phase II studies have showed that in the era of highly active antiretroviral therapy (HAART) the same regimens employed in HIV-negative patients with HL can be used in HIV setting with similar results. Moreover, in the last years the feasibility of high dose chemotherapy and peripheral stem cell rescue has allowed to save those patients who failed the upfront treatment. Finally, in the near future, a better integration of diagnostic tools (including PET scan), chemotherapy (including new drugs), radiotherapy, HAART, and supportive care will significantly improve the outcome of these patients.http://dx.doi.org/10.1155/2011/402682 |
| spellingShingle | Michele Spina Antonino Carbone Annunziata Gloghini Diego Serraino Massimiliano Berretta Umberto Tirelli Hodgkin's Disease in Patients with HIV Infection Advances in Hematology |
| title | Hodgkin's Disease in Patients with HIV Infection |
| title_full | Hodgkin's Disease in Patients with HIV Infection |
| title_fullStr | Hodgkin's Disease in Patients with HIV Infection |
| title_full_unstemmed | Hodgkin's Disease in Patients with HIV Infection |
| title_short | Hodgkin's Disease in Patients with HIV Infection |
| title_sort | hodgkin s disease in patients with hiv infection |
| url | http://dx.doi.org/10.1155/2011/402682 |
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