PDGF‐D Promotes Epithelial–Mesenchymal Transition of Glioma Cells Through the NF‐κB/NOTCH1 Pathway

PDGF‐D Promotes Epithelial–Mesenchymal Transition of Glioma Cells Through the NF‐κB/NOTCH1 Pathway

ABSTRACT Background Platelet‐derived growth factor‐D (PDGF‐D) is expressed at high levels in various tumors and is involved in epithelial–mesenchymal transition (EMT) and the malignant behavior of cancer cells. However, its role in glioma progression and the underlying molecular mechanisms remain un...

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Bibliographic Details
Main Authors: Yao Li, Yao Zhao, Minghao Shi, Xiaoshan Ma, Mingbo Jia, Zhongjun Shen, Xiaoyi Liu, Yunqian Li, Liyan Zhao
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Cancer Medicine
Subjects:
EMT
glioma
NF‐κB
NOTCH1
PDGF‐D
Online Access:https://doi.org/10.1002/cam4.71002
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