Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia

Schizophrenia is among top disability causes worldwide; however, its pathological mechanism is still unclear. In order to advance the research progress on schizophrenia, the Schizophrenia Imaging Lab has been dedicated to the diagnosis, treatment, and prevention of schizophrenia and conducted system...

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Main Authors: Tian-Cai Yan, Si-Wen Yu, Xian-Yang Wang, Lei Ren, Da Li, Wen-Yue Chu, Yan-Kun Han, Xin-Jiang Wang, Long-Biao Cui
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-09-01
Series:Meta-Radiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2950162824000407
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author Tian-Cai Yan
Si-Wen Yu
Xian-Yang Wang
Lei Ren
Da Li
Wen-Yue Chu
Yan-Kun Han
Xin-Jiang Wang
Long-Biao Cui
author_facet Tian-Cai Yan
Si-Wen Yu
Xian-Yang Wang
Lei Ren
Da Li
Wen-Yue Chu
Yan-Kun Han
Xin-Jiang Wang
Long-Biao Cui
author_sort Tian-Cai Yan
collection DOAJ
description Schizophrenia is among top disability causes worldwide; however, its pathological mechanism is still unclear. In order to advance the research progress on schizophrenia, the Schizophrenia Imaging Lab has been dedicated to the diagnosis, treatment, and prevention of schizophrenia and conducted systematic studies. One of the recent studies involved the Allen Human Brain Atlas in the imaging study of schizophrenia. The combination of the two methods mitigated the gap between the human brain imaging and genetic mechanism, and enabled us to observe the transcriptome alterations and brain changes at the same time. This review concluded the studies that combined the imaging method and the Allen Human Brain Atlas application in schizophrenia. We aim to provide a holistic view of the brain changes in schizophrenia at the micro level.
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institution Kabale University
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language English
publishDate 2024-09-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Meta-Radiology
spelling doaj-art-ee974b0975984a04b9d31d872ffa0d322024-11-12T05:22:44ZengKeAi Communications Co., Ltd.Meta-Radiology2950-16282024-09-0123100087Allen Human Brain Atlas and magnetic resonance imaging in schizophreniaTian-Cai Yan0Si-Wen Yu1Xian-Yang Wang2Lei Ren3Da Li4Wen-Yue Chu5Yan-Kun Han6Xin-Jiang Wang7Long-Biao Cui8Department of Radiology, The Fourth Affiliated Hospital of Harbin Medical University, Heilongjiang Harbin 150000, ChinaDepartment of Radiology, The Fourth Affiliated Hospital of Harbin Medical University, Heilongjiang Harbin 150000, ChinaSchizophrenia Imaging Lab, Xijing 986 Hospital, Fourth Military Medical University, Xi'an 710054, ChinaMilitary Psychology Section, Logistics University of PAP, Tianjin 300309, ChinaSchizophrenia Imaging Lab, Xijing 986 Hospital, Fourth Military Medical University, Xi'an 710054, ChinaSchizophrenia Imaging Lab, Xijing 986 Hospital, Fourth Military Medical University, Xi'an 710054, ChinaSchizophrenia Imaging Lab, Xijing 986 Hospital, Fourth Military Medical University, Xi'an 710054, ChinaDepartment of Radiology, The Second Medical Center, Chinese PLA General Hospital, Beijing 100853, China; Corresponding authors.Schizophrenia Imaging Lab, Xijing 986 Hospital, Fourth Military Medical University, Xi'an 710054, China; Department of Radiology, The Second Medical Center, Chinese PLA General Hospital, Beijing 100853, China; Department of Radiology, The First Affiliated Hospital of Xi'an Jiaotong University 710061, China; Shaanxi Provincial Key Laboratory of Clinic Genetics, Fourth Military Medical University, Xi'an 710032, China; Corresponding authors.Schizophrenia is among top disability causes worldwide; however, its pathological mechanism is still unclear. In order to advance the research progress on schizophrenia, the Schizophrenia Imaging Lab has been dedicated to the diagnosis, treatment, and prevention of schizophrenia and conducted systematic studies. One of the recent studies involved the Allen Human Brain Atlas in the imaging study of schizophrenia. The combination of the two methods mitigated the gap between the human brain imaging and genetic mechanism, and enabled us to observe the transcriptome alterations and brain changes at the same time. This review concluded the studies that combined the imaging method and the Allen Human Brain Atlas application in schizophrenia. We aim to provide a holistic view of the brain changes in schizophrenia at the micro level.http://www.sciencedirect.com/science/article/pii/S2950162824000407
spellingShingle Tian-Cai Yan
Si-Wen Yu
Xian-Yang Wang
Lei Ren
Da Li
Wen-Yue Chu
Yan-Kun Han
Xin-Jiang Wang
Long-Biao Cui
Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia
Meta-Radiology
title Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia
title_full Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia
title_fullStr Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia
title_full_unstemmed Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia
title_short Allen Human Brain Atlas and magnetic resonance imaging in schizophrenia
title_sort allen human brain atlas and magnetic resonance imaging in schizophrenia
url http://www.sciencedirect.com/science/article/pii/S2950162824000407
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