Recombinant adenovirus expressing pdhβ-pdhD fusion protein produces robust immune responses and partial protection against Mycoplasma Synoviae challenge in chickens

Recombinant adenovirus expressing pdhβ-pdhD fusion protein produces robust immune responses and partial protection against Mycoplasma Synoviae challenge in chickens

Mycoplasma synoviae (MS) stands as a pivotal pathogen, responsible for triggering arthritis and airsacculitis in both chickens and turkeys. Given the pressing need for safe and efficacious vaccine candidates, we engineered recombinant adenoviruses expressing a fusion antigen. This antigen consisted...

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Bibliographic Details
Main Authors: Li Ying-fen, Song Chun, Yue Jun, Han Shuai-bo, Chen Yu-jie, Wen Gui-lan, Wang Kai-gong, Shan Chun-lan, Zhu Er-peng, Cheng Zhen-tao
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Poultry Science
Subjects:
Mycoplasma synoviae
Recombinant adenovirus
pdhβ-pdhD fusion protein
Immunogenicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125004274
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