Correction of cholinergic deficiency in patients with vascular dementia
The efficacy of the acetylcholine esterase inhibitor reminil was studied in vascular dementia (VD). Eighty-four (54 men and 30 women) patients aged 60-85 years with the verified diagnosis of VD were followed up. Their mean age was 65±4,3 years; the mean duration of VD after its diagnosis was 2,3 yea...
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2010-06-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
| Subjects: | |
| Online Access: | https://nnp.ima-press.net/nnp/article/view/38 |
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| Summary: | The efficacy of the acetylcholine esterase inhibitor reminil was studied in vascular dementia (VD). Eighty-four (54 men and 30 women) patients aged 60-85 years with the verified diagnosis of VD were followed up. Their mean age was 65±4,3 years; the mean duration of VD after its diagnosis was 2,3 years (that after firstly detected VD was less than 4 years). Primary examination before therapy showed that all the patients had cognitive disorders characteristic of VD concurrent with varying motor disorders. Reminil showed a significant effect against the symptoms of VS within 1,5-2 months after initiation of its administration and when the therapeutic effect of the drug was achieved. Improved cognitive functions were preserved during a 12-month follow-up. Owing to its double mechanism of action, reminil is active against cognitive and behavioral disorders in a wide circle of patients with dementia, well tolerated, and causes no serious adverse reactions. |
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| ISSN: | 2074-2711 2310-1342 |