Further In Vitro and Ex Vivo Pharmacological and Kinetic Characterizations of CCF219B: A Positive Allosteric Modulator of the α<sub>1A</sub>-Adrenergic Receptor
<b>Background:</b> Alterations in the adrenergic system have been associated with the pathophysiology of Alzheimer’s disease (AD). A novel α<sub>1A</sub>-adrenergic receptor (AR)-positive allosteric modulator (PAM), CCF219B, has been shown to outperform donepezil with rescue...
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| Main Authors: | Robert S. Papay, Dianne M. Perez |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-03-01
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| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/18/4/476 |
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