Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives
We focused on a paper titled “Radiation with immunotherapy may be a double-edged sword—how can we learn from recent negative clinical trials?”, which was published in JAMA Oncology recently. Herein, we initially provided three complementary viewpoints from biological perspectives involved in the dyn...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578486/full |
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| _version_ | 1849225292031197184 |
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| author | Yanmei Liu Ganghui Ye Weijun Chen Yan Ding Shenpeng Ying Shixiu Wu |
| author_facet | Yanmei Liu Ganghui Ye Weijun Chen Yan Ding Shenpeng Ying Shixiu Wu |
| author_sort | Yanmei Liu |
| collection | DOAJ |
| description | We focused on a paper titled “Radiation with immunotherapy may be a double-edged sword—how can we learn from recent negative clinical trials?”, which was published in JAMA Oncology recently. Herein, we initially provided three complementary viewpoints from biological perspectives involved in the dynamic alterations of the tumor microenvironment, which may contribute to a more comprehensive understanding of the superiority of stereotactic body radiation therapy (SBRT). |
| format | Article |
| id | doaj-art-ee782daad52143a2928960a45a6a50ba |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-ee782daad52143a2928960a45a6a50ba2025-08-25T05:25:36ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-08-011610.3389/fimmu.2025.15784861578486Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectivesYanmei LiuGanghui YeWeijun ChenYan DingShenpeng YingShixiu WuWe focused on a paper titled “Radiation with immunotherapy may be a double-edged sword—how can we learn from recent negative clinical trials?”, which was published in JAMA Oncology recently. Herein, we initially provided three complementary viewpoints from biological perspectives involved in the dynamic alterations of the tumor microenvironment, which may contribute to a more comprehensive understanding of the superiority of stereotactic body radiation therapy (SBRT).https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578486/fullSBRTtumor microenvironmentradiosensitivityimmunotherapyimmune checkpoint inhibitors |
| spellingShingle | Yanmei Liu Ganghui Ye Weijun Chen Yan Ding Shenpeng Ying Shixiu Wu Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives Frontiers in Immunology SBRT tumor microenvironment radiosensitivity immunotherapy immune checkpoint inhibitors |
| title | Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives |
| title_full | Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives |
| title_fullStr | Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives |
| title_full_unstemmed | Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives |
| title_short | Stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors? From biological perspectives |
| title_sort | stereotactic body radiation therapy or conventional fractionated radiotherapy combined with immune checkpoint inhibitors from biological perspectives |
| topic | SBRT tumor microenvironment radiosensitivity immunotherapy immune checkpoint inhibitors |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578486/full |
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