Lymphoma or Brucellosis: A Case Series Study

Human Brucellosis is a zoonotic disease with various clinical manifestations, ranging from asymptomatic infection to multisystem involvement. Cases with hematological abnormalities and lymphadenopathy, which were referred to the hematology department of the hospital, were described from September 2...

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Main Authors: Parsa Rostami, Shiva Shabani, Azin Ahmari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-02-01
Series:Case Reports in Clinical Practice
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Online Access:https://crcp.tums.ac.ir/index.php/crcp/article/view/902
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author Parsa Rostami
Shiva Shabani
Azin Ahmari
author_facet Parsa Rostami
Shiva Shabani
Azin Ahmari
author_sort Parsa Rostami
collection DOAJ
description Human Brucellosis is a zoonotic disease with various clinical manifestations, ranging from asymptomatic infection to multisystem involvement. Cases with hematological abnormalities and lymphadenopathy, which were referred to the hematology department of the hospital, were described from September 2021 to August 2022. These Iranian patients included a 38-year-old man and two 64- and 24-year-old women. Due to the region’s endemicity and strong clinical suspicion of brucellosis, therapeutic management and invasive procedures such as splenectomy were avoided in one case. Based on the available literature, it is evident that the infrequent symptoms that accompany the typical symptoms of brucellosis may give rise to uncertainty and hinder prompt diagnosis. The reason is that patients presenting with indications of pancytopenia, coupled with splenomegaly or lymphadenopathy, are typically referred to hematologists. Hence, the purpose of these case reports is to highlight the symptoms of brucellosis that mimic a primary hematologic disorder, facilitating faster and more accurate diagnosis.
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spelling doaj-art-ee753d8dc3ea47ee957fc14c5f61586c2025-08-20T01:57:40ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912025-02-019410.18502/crcp.v9i4.17978Lymphoma or Brucellosis: A Case Series StudyParsa Rostami0Shiva Shabani1Azin Ahmari2Clinical Research Development Unit of Ayatollah-Khansari Hospital, Arak University of Medical Sciences, Arak, Iran. AND Department of Internal Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran.Clinical Research Development Unit of Ayatollah-Khansari Hospital, Arak University of Medical Sciences, Arak, Iran. AND Department of Infectious Diseases, School of Medicine, Arak University of Medical Sciences, Arak, Iran.Clinical Research Development Unit of Ayatollah-Khansari Hospital, Arak University of Medical Sciences, Arak, Iran. Human Brucellosis is a zoonotic disease with various clinical manifestations, ranging from asymptomatic infection to multisystem involvement. Cases with hematological abnormalities and lymphadenopathy, which were referred to the hematology department of the hospital, were described from September 2021 to August 2022. These Iranian patients included a 38-year-old man and two 64- and 24-year-old women. Due to the region’s endemicity and strong clinical suspicion of brucellosis, therapeutic management and invasive procedures such as splenectomy were avoided in one case. Based on the available literature, it is evident that the infrequent symptoms that accompany the typical symptoms of brucellosis may give rise to uncertainty and hinder prompt diagnosis. The reason is that patients presenting with indications of pancytopenia, coupled with splenomegaly or lymphadenopathy, are typically referred to hematologists. Hence, the purpose of these case reports is to highlight the symptoms of brucellosis that mimic a primary hematologic disorder, facilitating faster and more accurate diagnosis. https://crcp.tums.ac.ir/index.php/crcp/article/view/902BrucellosisLymphomaLymphadenopathy
spellingShingle Parsa Rostami
Shiva Shabani
Azin Ahmari
Lymphoma or Brucellosis: A Case Series Study
Case Reports in Clinical Practice
Brucellosis
Lymphoma
Lymphadenopathy
title Lymphoma or Brucellosis: A Case Series Study
title_full Lymphoma or Brucellosis: A Case Series Study
title_fullStr Lymphoma or Brucellosis: A Case Series Study
title_full_unstemmed Lymphoma or Brucellosis: A Case Series Study
title_short Lymphoma or Brucellosis: A Case Series Study
title_sort lymphoma or brucellosis a case series study
topic Brucellosis
Lymphoma
Lymphadenopathy
url https://crcp.tums.ac.ir/index.php/crcp/article/view/902
work_keys_str_mv AT parsarostami lymphomaorbrucellosisacaseseriesstudy
AT shivashabani lymphomaorbrucellosisacaseseriesstudy
AT azinahmari lymphomaorbrucellosisacaseseriesstudy