In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration

In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration

Inherited retinal diseases (IRDs) are clinically and genetically heterogeneous disorders characterized by progressive photoreceptor degeneration and irreversible vision loss. MicroRNAs (miRNAs), a class of endogenous non-coding RNAs with post-transcriptional regulatory properties, are known to play...

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Bibliographic Details
Main Authors: Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs
inherited retinal diseases
photoreceptor degeneration
microRNA
high-content screening
light-induced degeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253124003214
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