Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer
Management of locally advanced rectal cancer is complex, and magnetic resonance imaging (MRI) findings play a central role in treatment decisions. While neoadjuvant chemoradiotherapy significantly improved local recurrence rates, newer treatment modalities, such as total neoadjuvant chemotherapy, im...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2025-05-01
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| Series: | Journal of Gastrointestinal and Abdominal Radiology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1802595 |
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| _version_ | 1849425917511729152 |
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| author | Anuradha Chandramohan Antony Augustine Sneha Hiriyanna Shobiga Natarajan Ajeet A. Selvam Kurian C. Eapen Saloni A. Yadav Joseph Chacko Paul Aisha Lakhani Betty Simon Anu Eapen |
| author_facet | Anuradha Chandramohan Antony Augustine Sneha Hiriyanna Shobiga Natarajan Ajeet A. Selvam Kurian C. Eapen Saloni A. Yadav Joseph Chacko Paul Aisha Lakhani Betty Simon Anu Eapen |
| author_sort | Anuradha Chandramohan |
| collection | DOAJ |
| description | Management of locally advanced rectal cancer is complex, and magnetic resonance imaging (MRI) findings play a central role in treatment decisions. While neoadjuvant chemoradiotherapy significantly improved local recurrence rates, newer treatment modalities, such as total neoadjuvant chemotherapy, improved distant control. They significantly improved pathological complete response rates, enabling organ preservation in more patients. MRI is the best imaging modality to assess treatment response. MRI aids in assessing operability, predicts surgical outcomes following neoadjuvant treatment, and aids in identifying patients' eligible for organ preservation and their follow-up. In this review, we discuss imaging techniques and interpretation of rectal cancer MRI following neoadjuvant treatment, provide a structured reporting template for response assessment MRI, and detail how imaging findings influence treatment decisions. |
| format | Article |
| id | doaj-art-ee6f4ecc6da245cf9454f5a5311e009c |
| institution | Kabale University |
| issn | 2581-9178 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Gastrointestinal and Abdominal Radiology |
| spelling | doaj-art-ee6f4ecc6da245cf9454f5a5311e009c2025-08-20T03:29:35ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Gastrointestinal and Abdominal Radiology2581-91782025-05-01080209110710.1055/s-0045-1802595Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal CancerAnuradha Chandramohan0https://orcid.org/0000-0001-9093-375XAntony Augustine1Sneha Hiriyanna2Shobiga Natarajan3Ajeet A. Selvam4Kurian C. Eapen5Saloni A. Yadav6Joseph Chacko Paul7Aisha Lakhani8Betty Simon9Anu Eapen10Abdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaDepartment of Radiology, Luton and Dunstable University Hospital, Luton, United KingdomAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaAbdominal Imaging Unit, Department of Radiology, Christian Medical College Vellore, Tamil Nadu, IndiaManagement of locally advanced rectal cancer is complex, and magnetic resonance imaging (MRI) findings play a central role in treatment decisions. While neoadjuvant chemoradiotherapy significantly improved local recurrence rates, newer treatment modalities, such as total neoadjuvant chemotherapy, improved distant control. They significantly improved pathological complete response rates, enabling organ preservation in more patients. MRI is the best imaging modality to assess treatment response. MRI aids in assessing operability, predicts surgical outcomes following neoadjuvant treatment, and aids in identifying patients' eligible for organ preservation and their follow-up. In this review, we discuss imaging techniques and interpretation of rectal cancer MRI following neoadjuvant treatment, provide a structured reporting template for response assessment MRI, and detail how imaging findings influence treatment decisions.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1802595MRIrectal cancerMDTrestagingneoadjuvant chemoradiotherapy |
| spellingShingle | Anuradha Chandramohan Antony Augustine Sneha Hiriyanna Shobiga Natarajan Ajeet A. Selvam Kurian C. Eapen Saloni A. Yadav Joseph Chacko Paul Aisha Lakhani Betty Simon Anu Eapen Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer Journal of Gastrointestinal and Abdominal Radiology MRI rectal cancer MDT restaging neoadjuvant chemoradiotherapy |
| title | Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer |
| title_full | Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer |
| title_fullStr | Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer |
| title_full_unstemmed | Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer |
| title_short | Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer |
| title_sort | response assessment after neoadjuvant chemoradiotherapy in rectal cancer |
| topic | MRI rectal cancer MDT restaging neoadjuvant chemoradiotherapy |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0045-1802595 |
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