Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff
Purpose. To investigate the function and morphology of meibomian glands (MG) in night shift medical staff (MS). Methods. Sixty-two eyes of 31 patients in the MS group and 59 eyes of 31 patients in the control group were consecutively enrolled. All participants completed Ocular Surface Disease Index...
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| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/3275143 |
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| author | Jing Zhang Zhengzheng Wu Liangnan Sun Xin-hua Liu |
| author_facet | Jing Zhang Zhengzheng Wu Liangnan Sun Xin-hua Liu |
| author_sort | Jing Zhang |
| collection | DOAJ |
| description | Purpose. To investigate the function and morphology of meibomian glands (MG) in night shift medical staff (MS). Methods. Sixty-two eyes of 31 patients in the MS group and 59 eyes of 31 patients in the control group were consecutively enrolled. All participants completed Ocular Surface Disease Index (OSDI) and Standard Patient Dry Eye Evaluation (SPEED) questionnaires for dry eye severity, as well as Schirmer I and tear break-up time (TBUT) tests. LipiView® II Ocular Surface Interferometer was used for lipid layer thickness (LLT), MG dropout, and partial blink (PB) rate tests. MG expression was measured with an MG evaluator. Results. The OSDI score in the MS group was 22.39 ± 13.42, which was significantly higher than that in the control group (9.87 ± 6.64 Z = −3.997, P=0.001). The SPEED score in the MS group was 7.94 ± 3.81, which was significantly higher than in the control group (3.65 ± 2.11, Z = −4.766, P=0.001). There was no significant difference in Schirmer I test between the MS group and control group (Z = −1.346, P=0.178). TBUT in MS group was significantly shorter than that in the control group (Z = −5.201, P=0.001). The mean LLT of the MS group was 55.02 ± 21.17 nm significantly thinner than that of the control group 72.76 ± 21.62 nm (Z = −4.482, P=0.001). MG loss occurred in 45.16% of affected eyes in the MS group and 16.13% of affected eyes in the control group, and the difference was statistically significant (χ2 = 14.352, P=0.001). MG yielding liquid secretion and MG yielding secretion score were significantly lower in the MS group than in the control group (Z = −3.641, P=0.001; Z = −3.146, P=0.001, resp.). There was a negative correlation between mean LLT and SPEED score (Spearman r = −0.363, P=0.045). Conclusions. Night shift MS had a higher incidence of MGD compared to day workers. |
| format | Article |
| id | doaj-art-ee69986e24ec46b09270ebcd42340503 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-ee69986e24ec46b09270ebcd423405032025-02-03T06:46:51ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/32751433275143Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical StaffJing Zhang0Zhengzheng Wu1Liangnan Sun2Xin-hua Liu3Shenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen. No. 18, Zetian Road, Futian District, Shenzhen 518040, Guangdong, ChinaDepartment of Ophthalmology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu 610072, ChinaShenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen. No. 18, Zetian Road, Futian District, Shenzhen 518040, Guangdong, ChinaShenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen. No. 18, Zetian Road, Futian District, Shenzhen 518040, Guangdong, ChinaPurpose. To investigate the function and morphology of meibomian glands (MG) in night shift medical staff (MS). Methods. Sixty-two eyes of 31 patients in the MS group and 59 eyes of 31 patients in the control group were consecutively enrolled. All participants completed Ocular Surface Disease Index (OSDI) and Standard Patient Dry Eye Evaluation (SPEED) questionnaires for dry eye severity, as well as Schirmer I and tear break-up time (TBUT) tests. LipiView® II Ocular Surface Interferometer was used for lipid layer thickness (LLT), MG dropout, and partial blink (PB) rate tests. MG expression was measured with an MG evaluator. Results. The OSDI score in the MS group was 22.39 ± 13.42, which was significantly higher than that in the control group (9.87 ± 6.64 Z = −3.997, P=0.001). The SPEED score in the MS group was 7.94 ± 3.81, which was significantly higher than in the control group (3.65 ± 2.11, Z = −4.766, P=0.001). There was no significant difference in Schirmer I test between the MS group and control group (Z = −1.346, P=0.178). TBUT in MS group was significantly shorter than that in the control group (Z = −5.201, P=0.001). The mean LLT of the MS group was 55.02 ± 21.17 nm significantly thinner than that of the control group 72.76 ± 21.62 nm (Z = −4.482, P=0.001). MG loss occurred in 45.16% of affected eyes in the MS group and 16.13% of affected eyes in the control group, and the difference was statistically significant (χ2 = 14.352, P=0.001). MG yielding liquid secretion and MG yielding secretion score were significantly lower in the MS group than in the control group (Z = −3.641, P=0.001; Z = −3.146, P=0.001, resp.). There was a negative correlation between mean LLT and SPEED score (Spearman r = −0.363, P=0.045). Conclusions. Night shift MS had a higher incidence of MGD compared to day workers.http://dx.doi.org/10.1155/2020/3275143 |
| spellingShingle | Jing Zhang Zhengzheng Wu Liangnan Sun Xin-hua Liu Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff Journal of Ophthalmology |
| title | Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff |
| title_full | Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff |
| title_fullStr | Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff |
| title_full_unstemmed | Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff |
| title_short | Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff |
| title_sort | function and morphology of the meibomian glands using a lipiview interferometer in rotating shift medical staff |
| url | http://dx.doi.org/10.1155/2020/3275143 |
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