The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough

Coughing as the main symptom of a chronic cough is a persistent respiratory disease that poses a substantial challenge to Western medicine and traditional Chinese medicine (TCM). The Large Intestine and Lung are intimately related, impacting each other's pathology and physiology, according to T...

Full description

Saved in:
Bibliographic Details
Main Authors: Meng Yuan, Hongyuan Chen, Wen Rui
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-09-01
Series:Journal of Holistic Integrative Pharmacy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2707368824000499
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850194485187706880
author Meng Yuan
Hongyuan Chen
Wen Rui
author_facet Meng Yuan
Hongyuan Chen
Wen Rui
author_sort Meng Yuan
collection DOAJ
description Coughing as the main symptom of a chronic cough is a persistent respiratory disease that poses a substantial challenge to Western medicine and traditional Chinese medicine (TCM). The Large Intestine and Lung are intimately related, impacting each other's pathology and physiology, according to TCM theory. This complex interaction emphasizes how crucial it is to treat both organs at the same time while treating cough to support gut health. This viewpoint is further supported by current research, which demonstrates the connections between the Large Intestine and the Lung through a variety of pathways, including neurological pathways, mucosal immune system modulation, gas exchange dynamics, and microbiota composition. To clarify the mechanisms and practical applications of treating chronic cough by concurrently targeting the Lung and Intestine in TCM, this paper merges ideas from TCM theory and empirical research in Western medicine. This provides insightful information for efficiently managing chronic cough.
format Article
id doaj-art-ee5df182ec3a442a9e526dda1d5ad501
institution OA Journals
issn 2707-3688
language English
publishDate 2024-09-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Journal of Holistic Integrative Pharmacy
spelling doaj-art-ee5df182ec3a442a9e526dda1d5ad5012025-08-20T02:13:59ZengKeAi Communications Co., Ltd.Journal of Holistic Integrative Pharmacy2707-36882024-09-015319520410.1016/j.jhip.2024.09.004The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic coughMeng Yuan0Hongyuan Chen1Wen Rui2Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, ChinaDepartment of Pathogen Biology and Immunology, School of Basic Medical Sciences, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Cosmetics Engineering & Technology Research Center, Guangzhou, 510006, ChinaCenter for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Engineering & Technology Research Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Cosmetics Engineering & Technology Research Center, Guangzhou, 510006, China; Corresponding author. Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China.Coughing as the main symptom of a chronic cough is a persistent respiratory disease that poses a substantial challenge to Western medicine and traditional Chinese medicine (TCM). The Large Intestine and Lung are intimately related, impacting each other's pathology and physiology, according to TCM theory. This complex interaction emphasizes how crucial it is to treat both organs at the same time while treating cough to support gut health. This viewpoint is further supported by current research, which demonstrates the connections between the Large Intestine and the Lung through a variety of pathways, including neurological pathways, mucosal immune system modulation, gas exchange dynamics, and microbiota composition. To clarify the mechanisms and practical applications of treating chronic cough by concurrently targeting the Lung and Intestine in TCM, this paper merges ideas from TCM theory and empirical research in Western medicine. This provides insightful information for efficiently managing chronic cough.http://www.sciencedirect.com/science/article/pii/S2707368824000499Lung-gut axisChronic coughTraditional Chinese medicine treatment
spellingShingle Meng Yuan
Hongyuan Chen
Wen Rui
The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
Journal of Holistic Integrative Pharmacy
Lung-gut axis
Chronic cough
Traditional Chinese medicine treatment
title The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
title_full The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
title_fullStr The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
title_full_unstemmed The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
title_short The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
title_sort research advance on the theory of chinese medicine exterior interior correlation between the lung and large intestine in the treatment of chronic cough
topic Lung-gut axis
Chronic cough
Traditional Chinese medicine treatment
url http://www.sciencedirect.com/science/article/pii/S2707368824000499
work_keys_str_mv AT mengyuan theresearchadvanceonthetheoryofchinesemedicineexteriorinteriorcorrelationbetweenthelungandlargeintestineinthetreatmentofchroniccough
AT hongyuanchen theresearchadvanceonthetheoryofchinesemedicineexteriorinteriorcorrelationbetweenthelungandlargeintestineinthetreatmentofchroniccough
AT wenrui theresearchadvanceonthetheoryofchinesemedicineexteriorinteriorcorrelationbetweenthelungandlargeintestineinthetreatmentofchroniccough
AT mengyuan researchadvanceonthetheoryofchinesemedicineexteriorinteriorcorrelationbetweenthelungandlargeintestineinthetreatmentofchroniccough
AT hongyuanchen researchadvanceonthetheoryofchinesemedicineexteriorinteriorcorrelationbetweenthelungandlargeintestineinthetreatmentofchroniccough
AT wenrui researchadvanceonthetheoryofchinesemedicineexteriorinteriorcorrelationbetweenthelungandlargeintestineinthetreatmentofchroniccough