An optimized Langendorff-free isolating method and electrophysiology studies for adult mouse atrioventricular node cells

Abstract Background The atrioventricular node (AVN) plays a critical role in coordinating the sequential activation and contraction of the heart’s chambers by transmitting electrical impulses from the sinoatrial node (SAN) to the ventricles via the His-Purkinje system. Besides its primary function,...

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Main Authors: Yuan Chen, Jiaming Zhang, Jiu Pu, Ting Li, Jinfang Yu, Bifang Mai, Shuanglun Xie, Jingdong Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cardiovascular Disorders
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Online Access:https://doi.org/10.1186/s12872-025-04888-1
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