Fasting Upregulates PPAR𝛼 Target Genes in Brain and Influences Pituitary Hormone Expression in a PPAR𝛼 Dependent Manner

Fasting Upregulates PPAR𝛼 Target Genes in Brain and Influences Pituitary Hormone Expression in a PPAR𝛼 Dependent Manner

PPAR𝛼 is a lipid-activable transcription factor that mediates the adaptive response to fasting. Recent data indicate an important role of brain PPAR𝛼 in physiological functions. However, it has not yet been shown whether PPAR𝛼 in brain can be activated in the fasting state. Here we demonstrate...

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Bibliographic Details
Main Authors: Bettina König, Christine Rauer, Susann Rosenbaum, Corinna Brandsch, Klaus Eder, Gabriele I. Stangl
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2009/801609
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