Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications
ObjectivesThis study aimed to explore the potential of synchronously acquiring wrist pressure pulse wave (PPW) and limb lead electrocardiogram (ECG) signals for the development of an identification model for coronary heart disease (CHD) and its associated comorbidities.MethodsA custom-designed devic...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2025.1628309/full |
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| author | Lei-Xin Hong Wen-Jie Wu Xia Chen Dan-Qun Xiong Ye-Qing Zhang Xiang-Dong Xu Jian-Jun Yan Rui Guo |
| author_facet | Lei-Xin Hong Wen-Jie Wu Xia Chen Dan-Qun Xiong Ye-Qing Zhang Xiang-Dong Xu Jian-Jun Yan Rui Guo |
| author_sort | Lei-Xin Hong |
| collection | DOAJ |
| description | ObjectivesThis study aimed to explore the potential of synchronously acquiring wrist pressure pulse wave (PPW) and limb lead electrocardiogram (ECG) signals for the development of an identification model for coronary heart disease (CHD) and its associated comorbidities.MethodsA custom-designed device equipped with pressure and ECG sensors, was utilized to synchronously collect wrist PPW and limb-lead ECG signals from 748 participants (463 for modeling and 285 for external validation). Features were extracted from these two types of physiological signals to form distinct datasets, and RF models were built based on different datasets. The top-performing RF model was then selected and compared against the Feature-Selected (FS-RF), Support Vector Machine (SVM) and Bagged Decision Tree (BDT) models. Ultimately, the optimal model for predicting coronary heart disease (CHD) and its comorbidity was determined based on evaluation metrics.ResultsThe RF model that integrated both PPW and ECG features demonstrated significantly higher effectiveness compared to the RF model that relied on a single physiological signal. Furthermore, when benchmarked against the feature-selected RF(FS-RF), SVM and DBT models, the FS-RF model demonstrated the best performance, achieving an accuracy of 76.32%, an average precision of 75.82%, an average recall of 76.11%, and an average F1-score of 75.88%, all of which were higher than those of other models. Notably, the selected feature by FS-RF encompassed both PPW and ECG features.ConclusionThis study highlights the importance of synchronously acquiring of PPW and ECG signal, along with feature selection, in enhancing the performance of the FS-RF model for identifying CHD and its associated conditions. These findings provide a scientific basis for the application of wearable devices in clinical settings, highlighting their potential to aid in the early detection and management of cardiovascular disease. |
| format | Article |
| id | doaj-art-ee3bf9a744cd428a83a29e4af839230a |
| institution | Kabale University |
| issn | 1664-042X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj-art-ee3bf9a744cd428a83a29e4af839230a2025-08-20T03:31:52ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2025-07-011610.3389/fphys.2025.16283091628309Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complicationsLei-Xin Hong0Wen-Jie Wu1Xia Chen2Dan-Qun Xiong3Ye-Qing Zhang4Xiang-Dong Xu5Jian-Jun Yan6Rui Guo7School of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaSchool of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Cardiology, Shanghai Jiading District Central Hospital, Shanghai, ChinaDepartment of Cardiology, Shanghai Jiading District Central Hospital, Shanghai, ChinaDepartment of Chinese Internal Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Cardiology, Shanghai Jiading District Central Hospital, Shanghai, ChinaSchool of Mechanical and Power Engineering, Institute of Intelligent Perception and Diagnosis, East China University of Science and Technology, Shanghai, ChinaSchool of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaObjectivesThis study aimed to explore the potential of synchronously acquiring wrist pressure pulse wave (PPW) and limb lead electrocardiogram (ECG) signals for the development of an identification model for coronary heart disease (CHD) and its associated comorbidities.MethodsA custom-designed device equipped with pressure and ECG sensors, was utilized to synchronously collect wrist PPW and limb-lead ECG signals from 748 participants (463 for modeling and 285 for external validation). Features were extracted from these two types of physiological signals to form distinct datasets, and RF models were built based on different datasets. The top-performing RF model was then selected and compared against the Feature-Selected (FS-RF), Support Vector Machine (SVM) and Bagged Decision Tree (BDT) models. Ultimately, the optimal model for predicting coronary heart disease (CHD) and its comorbidity was determined based on evaluation metrics.ResultsThe RF model that integrated both PPW and ECG features demonstrated significantly higher effectiveness compared to the RF model that relied on a single physiological signal. Furthermore, when benchmarked against the feature-selected RF(FS-RF), SVM and DBT models, the FS-RF model demonstrated the best performance, achieving an accuracy of 76.32%, an average precision of 75.82%, an average recall of 76.11%, and an average F1-score of 75.88%, all of which were higher than those of other models. Notably, the selected feature by FS-RF encompassed both PPW and ECG features.ConclusionThis study highlights the importance of synchronously acquiring of PPW and ECG signal, along with feature selection, in enhancing the performance of the FS-RF model for identifying CHD and its associated conditions. These findings provide a scientific basis for the application of wearable devices in clinical settings, highlighting their potential to aid in the early detection and management of cardiovascular disease.https://www.frontiersin.org/articles/10.3389/fphys.2025.1628309/fullcoronary heart diseasecomplicationssynchronous acquisition of ECG and PPWmachine learning algorithmsmodeling |
| spellingShingle | Lei-Xin Hong Wen-Jie Wu Xia Chen Dan-Qun Xiong Ye-Qing Zhang Xiang-Dong Xu Jian-Jun Yan Rui Guo Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications Frontiers in Physiology coronary heart disease complications synchronous acquisition of ECG and PPW machine learning algorithms modeling |
| title | Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications |
| title_full | Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications |
| title_fullStr | Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications |
| title_full_unstemmed | Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications |
| title_short | Fusing wrist pulse and ECG data for enhanced identification of coronary heart disease and its complications |
| title_sort | fusing wrist pulse and ecg data for enhanced identification of coronary heart disease and its complications |
| topic | coronary heart disease complications synchronous acquisition of ECG and PPW machine learning algorithms modeling |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2025.1628309/full |
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