Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis
<p><strong>Background: </strong>Smoke increases the development of many diseases. Previous studies about its role in the pathogenesis of acne shows contradictory results.</p><p><strong>Methods:</strong> A questionnaire was administrated to each participant,...
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| Format: | Article |
| Language: | English |
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Milano University Press
2015-02-01
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| Series: | Epidemiology, Biostatistics and Public Health |
| Online Access: | http://ebph.it/article/view/10987 |
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| author | Alice Mannocci Leda Semyonov Rosella Saulle Nevena Skroza Concetta Potenza Ersilia Tolino Antonio Boccia Giuseppe La Torre |
| author_facet | Alice Mannocci Leda Semyonov Rosella Saulle Nevena Skroza Concetta Potenza Ersilia Tolino Antonio Boccia Giuseppe La Torre |
| author_sort | Alice Mannocci |
| collection | DOAJ |
| description | <p><strong>Background: </strong>Smoke increases the development of many diseases. Previous studies about its role in the pathogenesis of acne shows contradictory results.</p><p><strong>Methods:</strong> A questionnaire was administrated to each participant, to assess the association acne - smoke. <strong>For the systematic review, a</strong> bibliographic search on electronic databases was performed (Pubmed, Scopus and Google Scholar). Only case-control studies in English-language from 1966 to 2010 were included. All publications were analyzed by two researchers. Data regarded acneic patients in current and never smokers. Quality assessment was performed using a score for observational study.</p><p><strong>Results:</strong> Of 93 cases of the case-control study, 6 patients had severe acne, 19 moderate acne and 68 had a mild acne, according to classification of Global Alliance to improve outcomes in acne. No one of the smokers had severe acne, only one smoker had moderate acne and 11 had mild acne. Systematic review considered five population studies. First meta-analysis, with all investigations, showed a OR=2.03 (95% CI: 0.63–6.58). The sensitivity analyses include meta-analyses stratified by gender, and quality (score>6). Results for males were: OR=1.89 (95%CI:1.25-2.87); for female OR=1.84 (95%CI:0.36-9.51). The analysis using quality score reported OR=3.48, (95%CI: 1.58-7.68).</p><p><strong>Conclusions: </strong>In conclusions, smokers have higher risk to develop acne, especially males. Conclusions are not robust, because of heterogeneity definitions of smokers and acne grading.</p><p><strong>Keywords: </strong>Acne; Smoke; Tobacco; Nicotine; Cigarettes.</p> |
| format | Article |
| id | doaj-art-ee3ae7df13f04bb2b9da5d79c037aae0 |
| institution | DOAJ |
| issn | 2282-0930 |
| language | English |
| publishDate | 2015-02-01 |
| publisher | Milano University Press |
| record_format | Article |
| series | Epidemiology, Biostatistics and Public Health |
| spelling | doaj-art-ee3ae7df13f04bb2b9da5d79c037aae02025-08-20T03:06:31ZengMilano University PressEpidemiology, Biostatistics and Public Health2282-09302015-02-0112110.2427/1098710353Association between smoking habits and acne. A case-control study and a systematic review and meta-analysisAlice Mannocci0Leda Semyonov1Rosella Saulle2Nevena Skroza3Concetta Potenza4Ersilia Tolino5Antonio Boccia6Giuseppe La Torre7Clinical Medicine and Public Health, Department of Public Health and Infectious Diseases, Sapienza University of RomeClinical Medicine and Public Health, Department of Public Health and Infectious Diseases, Sapienza University of RomeClinical Medicine and Public Health, Department of Public Health and Infectious Diseases, Sapienza University of RomeDermatology Unit “D. Innocenzi”, Polo Pontino, Sapienza University of RomeDermatology Unit “D. Innocenzi”, Polo Pontino, Sapienza University of RomeDermatology Unit “D. Innocenzi”, Polo Pontino, Sapienza University of RomeClinical Medicine and Public Health, Department of Public Health and Infectious Diseases, Sapienza University of RomeClinical Medicine and Public Health, Department of Public Health and Infectious Diseases, Sapienza University of Rome<p><strong>Background: </strong>Smoke increases the development of many diseases. Previous studies about its role in the pathogenesis of acne shows contradictory results.</p><p><strong>Methods:</strong> A questionnaire was administrated to each participant, to assess the association acne - smoke. <strong>For the systematic review, a</strong> bibliographic search on electronic databases was performed (Pubmed, Scopus and Google Scholar). Only case-control studies in English-language from 1966 to 2010 were included. All publications were analyzed by two researchers. Data regarded acneic patients in current and never smokers. Quality assessment was performed using a score for observational study.</p><p><strong>Results:</strong> Of 93 cases of the case-control study, 6 patients had severe acne, 19 moderate acne and 68 had a mild acne, according to classification of Global Alliance to improve outcomes in acne. No one of the smokers had severe acne, only one smoker had moderate acne and 11 had mild acne. Systematic review considered five population studies. First meta-analysis, with all investigations, showed a OR=2.03 (95% CI: 0.63–6.58). The sensitivity analyses include meta-analyses stratified by gender, and quality (score>6). Results for males were: OR=1.89 (95%CI:1.25-2.87); for female OR=1.84 (95%CI:0.36-9.51). The analysis using quality score reported OR=3.48, (95%CI: 1.58-7.68).</p><p><strong>Conclusions: </strong>In conclusions, smokers have higher risk to develop acne, especially males. Conclusions are not robust, because of heterogeneity definitions of smokers and acne grading.</p><p><strong>Keywords: </strong>Acne; Smoke; Tobacco; Nicotine; Cigarettes.</p>http://ebph.it/article/view/10987 |
| spellingShingle | Alice Mannocci Leda Semyonov Rosella Saulle Nevena Skroza Concetta Potenza Ersilia Tolino Antonio Boccia Giuseppe La Torre Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis Epidemiology, Biostatistics and Public Health |
| title | Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis |
| title_full | Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis |
| title_fullStr | Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis |
| title_full_unstemmed | Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis |
| title_short | Association between smoking habits and acne. A case-control study and a systematic review and meta-analysis |
| title_sort | association between smoking habits and acne a case control study and a systematic review and meta analysis |
| url | http://ebph.it/article/view/10987 |
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