Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate

The global swine industry faces significant challenges related to improving the survival and health of newborn piglets. Attention has come to β-hydroxy-β-methylbutyrate (HMB), a metabolite of leucine, for its potential in prenatal nutritional programming in sows, which can improve piglet body weight...

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Main Authors: Dajnowska Aleksandra, Kras Katarzyna, Tomaszewska Ewa, Dobrowolski Piotr, Klebaniuk Renata, Muszyński Siemowit, Arciszewski Marcin Bartłomiej
Format: Article
Language:English
Published: Sciendo 2025-04-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2025-0024
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author Dajnowska Aleksandra
Kras Katarzyna
Tomaszewska Ewa
Dobrowolski Piotr
Klebaniuk Renata
Muszyński Siemowit
Arciszewski Marcin Bartłomiej
author_facet Dajnowska Aleksandra
Kras Katarzyna
Tomaszewska Ewa
Dobrowolski Piotr
Klebaniuk Renata
Muszyński Siemowit
Arciszewski Marcin Bartłomiej
author_sort Dajnowska Aleksandra
collection DOAJ
description The global swine industry faces significant challenges related to improving the survival and health of newborn piglets. Attention has come to β-hydroxy-β-methylbutyrate (HMB), a metabolite of leucine, for its potential in prenatal nutritional programming in sows, which can improve piglet body weight and support the development of the skeletal and digestive systems. The effects of prenatal HMB supplementation were investigated on the chemical coding of the enteric nervous system (ENS) in the small intestine of neonatal piglets.
format Article
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issn 2450-8608
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publishDate 2025-04-01
publisher Sciendo
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series Journal of Veterinary Research
spelling doaj-art-ee29bb9059fe469984b1a69378fdf2702025-08-20T03:15:10ZengSciendoJournal of Veterinary Research2450-86082025-04-0169224925510.2478/jvetres-2025-0024Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrateDajnowska Aleksandra0Kras Katarzyna1Tomaszewska Ewa2Dobrowolski Piotr3Klebaniuk Renata4Muszyński Siemowit5Arciszewski Marcin Bartłomiej61Department of Animal Anatomy and Histology, Department of Animal Physiology, Institute of Animal Nutrition and Bromatology, Faculty of Veterinary Medicine, Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950Lublin, Poland1Department of Animal Anatomy and Histology, Department of Animal Physiology, Institute of Animal Nutrition and Bromatology, Faculty of Veterinary Medicine, Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950Lublin, Poland2Department of Animal Physiology, Institute of Animal Nutrition and Bromatology, Faculty of Veterinary Medicine, Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950Lublin, Poland3Department of Functional Anatomy and Cytobiology, Maria Curie-Skłodowska University, 20-033Lublin, Poland4Institute of Animal Nutrition and Bromatology, Faculty of Veterinary Medicine, Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950Lublin, Poland5Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950Lublin, Poland1Department of Animal Anatomy and Histology, Department of Animal Physiology, Institute of Animal Nutrition and Bromatology, Faculty of Veterinary Medicine, Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950Lublin, PolandThe global swine industry faces significant challenges related to improving the survival and health of newborn piglets. Attention has come to β-hydroxy-β-methylbutyrate (HMB), a metabolite of leucine, for its potential in prenatal nutritional programming in sows, which can improve piglet body weight and support the development of the skeletal and digestive systems. The effects of prenatal HMB supplementation were investigated on the chemical coding of the enteric nervous system (ENS) in the small intestine of neonatal piglets.https://doi.org/10.2478/jvetres-2025-0024enshmbpigsprenatal supplementationsmall intestine
spellingShingle Dajnowska Aleksandra
Kras Katarzyna
Tomaszewska Ewa
Dobrowolski Piotr
Klebaniuk Renata
Muszyński Siemowit
Arciszewski Marcin Bartłomiej
Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate
Journal of Veterinary Research
ens
hmb
pigs
prenatal supplementation
small intestine
title Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate
title_full Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate
title_fullStr Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate
title_full_unstemmed Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate
title_short Chemical coding of piglets small intestine neurons after prenatal exposure to β-hydroxy-β-methylbutyrate
title_sort chemical coding of piglets small intestine neurons after prenatal exposure to β hydroxy β methylbutyrate
topic ens
hmb
pigs
prenatal supplementation
small intestine
url https://doi.org/10.2478/jvetres-2025-0024
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