Myostatin/Smad2/Smad3 pathway define a differential clinical phenotype in COPD-associated sarcopenia

Myostatin/Smad2/Smad3 pathway define a differential clinical phenotype in COPD-associated sarcopenia

Background Sarcopenia, defined as the loss of muscle mass and function, represents one of the most relevant comorbidities in patients with COPD even at early stages. We hypothesised that sarcopenia defines a specific clinical phenotype in COPD irrespective of respiratory disease severity. Markers of...

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Main Authors: Adriana Núñez-Robainas, Maria Guitart, Adrián López-Postigo, Antonio Sancho-Muñoz, Esther Barreiro
Format: Article
Language:English
Published: European Respiratory Society 2025-04-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/11/2/00772-2024.full
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