ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE
Condensation of 6-methoxy benzothiazol-2-amine with 2-hydroxy- naphthaldehyde gave newSchiff-base derivative in good yield. The metal complex of Co(II) have been synthesized withSchiff base of benzothiazol derivative. Spectroscopic study such as, two dimensional NMR ofnew compound have been obtained...
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| Format: | Article |
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College of Veterinary Medicine, University of Basrah, Iraq
2015-03-01
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| Series: | Basrah Journal of Veterinary Research |
| Subjects: | |
| Online Access: | https://bjvr.uobasrah.edu.iq/article_174899_c8c50a6a2d4a5fccee165a46098fd3ed.pdf |
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| author | Wasfi A. Al-Masoudi Rasha M. Othman Rafid H. Al-Asadi Mohaned A. Ali |
| author_facet | Wasfi A. Al-Masoudi Rasha M. Othman Rafid H. Al-Asadi Mohaned A. Ali |
| author_sort | Wasfi A. Al-Masoudi |
| collection | DOAJ |
| description | Condensation of 6-methoxy benzothiazol-2-amine with 2-hydroxy- naphthaldehyde gave newSchiff-base derivative in good yield. The metal complex of Co(II) have been synthesized withSchiff base of benzothiazol derivative. Spectroscopic study such as, two dimensional NMR ofnew compound have been obtained by using nuclear magnatic resonance 600 MHz.Computational study of all compounds was calculated using Gaussian 09 program package. Thesynthesized compounds were screened for their antibacterial activity against Staphylococcusaureus, Escherichia coli, Bacillus subtilis, Klebsiella pneumonia. Additionally, the compoundswere tested for antifungal activity against Candida albicans, Candida tropica, Aspergillus multiand Aspergillus niger. Cobalt complex compound exhibited more activity as antifungal thanbenzothiazole derivative. |
| format | Article |
| id | doaj-art-ee294f57fba849afb329703ec7d4af4e |
| institution | OA Journals |
| issn | 1813-8497 2410-8456 |
| language | English |
| publishDate | 2015-03-01 |
| publisher | College of Veterinary Medicine, University of Basrah, Iraq |
| record_format | Article |
| series | Basrah Journal of Veterinary Research |
| spelling | doaj-art-ee294f57fba849afb329703ec7d4af4e2025-08-20T01:49:57ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562015-03-0115421422910.23975/bjvetr.2015.174899174899ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVEWasfi A. Al-Masoudi0Rasha M. Othman1Rafid H. Al-Asadi2Mohaned A. Ali3Department of Physiology, Pharmacology and Chemistry,College of Veterinary Medicine,University of Basrah,Basrah,iraq2Department of Microbiology, College of veterinary medicine,University of Basrah,Basrah,IraqDepartment of Chemistry, College of Education for pure sciences ,University of Basrah, IraqDepartment of Physiology, Pharmacology and Chemistry,College of Veterinary Medicine,University of Basrah,Basrah,iraqCondensation of 6-methoxy benzothiazol-2-amine with 2-hydroxy- naphthaldehyde gave newSchiff-base derivative in good yield. The metal complex of Co(II) have been synthesized withSchiff base of benzothiazol derivative. Spectroscopic study such as, two dimensional NMR ofnew compound have been obtained by using nuclear magnatic resonance 600 MHz.Computational study of all compounds was calculated using Gaussian 09 program package. Thesynthesized compounds were screened for their antibacterial activity against Staphylococcusaureus, Escherichia coli, Bacillus subtilis, Klebsiella pneumonia. Additionally, the compoundswere tested for antifungal activity against Candida albicans, Candida tropica, Aspergillus multiand Aspergillus niger. Cobalt complex compound exhibited more activity as antifungal thanbenzothiazole derivative.https://bjvr.uobasrah.edu.iq/article_174899_c8c50a6a2d4a5fccee165a46098fd3ed.pdfbenzothiazolnmr spectroscopycobalt complex |
| spellingShingle | Wasfi A. Al-Masoudi Rasha M. Othman Rafid H. Al-Asadi Mohaned A. Ali ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE Basrah Journal of Veterinary Research benzothiazol nmr spectroscopy cobalt complex |
| title | ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE |
| title_full | ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE |
| title_fullStr | ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE |
| title_full_unstemmed | ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE |
| title_short | ANTIMICROBIAL ACTIVITY AND COMPUTATIONAL STUDY OF NEW COBALT (II )COMPLEX OF BENZOTHIAZOLE DERIVATIVE |
| title_sort | antimicrobial activity and computational study of new cobalt ii complex of benzothiazole derivative |
| topic | benzothiazol nmr spectroscopy cobalt complex |
| url | https://bjvr.uobasrah.edu.iq/article_174899_c8c50a6a2d4a5fccee165a46098fd3ed.pdf |
| work_keys_str_mv | AT wasfiaalmasoudi antimicrobialactivityandcomputationalstudyofnewcobaltiicomplexofbenzothiazolederivative AT rashamothman antimicrobialactivityandcomputationalstudyofnewcobaltiicomplexofbenzothiazolederivative AT rafidhalasadi antimicrobialactivityandcomputationalstudyofnewcobaltiicomplexofbenzothiazolederivative AT mohanedaali antimicrobialactivityandcomputationalstudyofnewcobaltiicomplexofbenzothiazolederivative |