How endocrine disruptors affect fish reproduction on multiple levels: A review
This review paper presents fish reproductive toxicology studies with a specific focus on endocrine-disrupting chemicals (EDCs) present in the aquatic environment. These substances, including bisphenols, heavy metals, pesticides, phthalates, and polychlorinated biphenyls (PCBs), act as hormone mimics...
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| Format: | Article |
| Language: | English |
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Sciendo
2024-09-01
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| Series: | Fisheries & Aquatic Life |
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| Online Access: | https://doi.org/10.2478/aopf-2024-0012 |
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| author | Socha Magdalena Chyb Jarosław Suder Aleksandra Bojarski Bartosz |
| author_facet | Socha Magdalena Chyb Jarosław Suder Aleksandra Bojarski Bartosz |
| author_sort | Socha Magdalena |
| collection | DOAJ |
| description | This review paper presents fish reproductive toxicology studies with a specific focus on endocrine-disrupting chemicals (EDCs) present in the aquatic environment. These substances, including bisphenols, heavy metals, pesticides, phthalates, and polychlorinated biphenyls (PCBs), act as hormone mimics, receptor blockers, or enzyme inhibitors that affect hormonal regulation in the hypothalamic-pituitary-gonadal (HPG) axis. In this review, we provide an overview of the adverse effects of these pollutants on both female and male fish reproduction (i.e., hormonal disruption in the HPG axis, gametogenesis disorders, disturbed embryogenesis, etc.). Even at low concentrations, EDCs can exhibit reproductive toxicity in fishes. They can affect the functioning of certain systems within the hypothalamus (Kiss/GPR54, GnRH) and can also impact luteinizing hormone (LH) secretion in the pituitary. These compounds have negative impacts on gonads, oocyte maturation, steroidogenesis, and gametes. Early-life exposure to these substances not only affects embryonic development, resulting in increased mortality and body malformations, but this also induces genetic changes in newly hatched larvae. All these observations underscore the need for monitoring the aquatic environment for EDCs and implementing protective measures to preserve the health and welfare of fishes and safeguard water ecosystems. |
| format | Article |
| id | doaj-art-ee287ca1fa7748549fe9b3488a95c494 |
| institution | Kabale University |
| issn | 2545-059X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Fisheries & Aquatic Life |
| spelling | doaj-art-ee287ca1fa7748549fe9b3488a95c4942025-02-10T13:25:25ZengSciendoFisheries & Aquatic Life2545-059X2024-09-0132312813610.2478/aopf-2024-0012How endocrine disruptors affect fish reproduction on multiple levels: A reviewSocha Magdalena0Chyb Jarosław1Suder Aleksandra2Bojarski Bartosz31University of Agriculture in Krakow, Department of Animal Physiology and Endocrinology al. Mickiewicza 24/28, 31-059Krakow, Poland2University of Agriculture in Krakow, Department of Animal Nutrition and Biotechnology, and Fisheries ul. Profesora Spiczakowa 6, 30-199Krakow, Poland1University of Agriculture in Krakow, Department of Animal Physiology and Endocrinology al. Mickiewicza 24/28, 31-059Krakow, Poland3Department of Animal Physiology, Institute of Biology, Pomeranian University in Słupsk, Arciszewskiego 22b, 76-200Słupsk, PolandThis review paper presents fish reproductive toxicology studies with a specific focus on endocrine-disrupting chemicals (EDCs) present in the aquatic environment. These substances, including bisphenols, heavy metals, pesticides, phthalates, and polychlorinated biphenyls (PCBs), act as hormone mimics, receptor blockers, or enzyme inhibitors that affect hormonal regulation in the hypothalamic-pituitary-gonadal (HPG) axis. In this review, we provide an overview of the adverse effects of these pollutants on both female and male fish reproduction (i.e., hormonal disruption in the HPG axis, gametogenesis disorders, disturbed embryogenesis, etc.). Even at low concentrations, EDCs can exhibit reproductive toxicity in fishes. They can affect the functioning of certain systems within the hypothalamus (Kiss/GPR54, GnRH) and can also impact luteinizing hormone (LH) secretion in the pituitary. These compounds have negative impacts on gonads, oocyte maturation, steroidogenesis, and gametes. Early-life exposure to these substances not only affects embryonic development, resulting in increased mortality and body malformations, but this also induces genetic changes in newly hatched larvae. All these observations underscore the need for monitoring the aquatic environment for EDCs and implementing protective measures to preserve the health and welfare of fishes and safeguard water ecosystems.https://doi.org/10.2478/aopf-2024-0012pesticidesfishreproductionxenobioticembryos dysfunctions |
| spellingShingle | Socha Magdalena Chyb Jarosław Suder Aleksandra Bojarski Bartosz How endocrine disruptors affect fish reproduction on multiple levels: A review Fisheries & Aquatic Life pesticides fish reproduction xenobiotic embryos dysfunctions |
| title | How endocrine disruptors affect fish reproduction on multiple levels: A review |
| title_full | How endocrine disruptors affect fish reproduction on multiple levels: A review |
| title_fullStr | How endocrine disruptors affect fish reproduction on multiple levels: A review |
| title_full_unstemmed | How endocrine disruptors affect fish reproduction on multiple levels: A review |
| title_short | How endocrine disruptors affect fish reproduction on multiple levels: A review |
| title_sort | how endocrine disruptors affect fish reproduction on multiple levels a review |
| topic | pesticides fish reproduction xenobiotic embryos dysfunctions |
| url | https://doi.org/10.2478/aopf-2024-0012 |
| work_keys_str_mv | AT sochamagdalena howendocrinedisruptorsaffectfishreproductiononmultiplelevelsareview AT chybjarosław howendocrinedisruptorsaffectfishreproductiononmultiplelevelsareview AT suderaleksandra howendocrinedisruptorsaffectfishreproductiononmultiplelevelsareview AT bojarskibartosz howendocrinedisruptorsaffectfishreproductiononmultiplelevelsareview |