Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools

The rising prevalence of dementia, particularly in low-income and developing countries, highlights the urgent need for effective cognitive screening tools. However, the existing tools often fail to address the unique needs of low-educated and illiterate populations, leading to diagnostic disparities...

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Main Authors: Jonathan Adrián Zegarra-Valdivia, Brenda Chino, Kuripacha Tituana, Lina Zapata-Restrepo, María Martha Unaucho, Milton Lopez-Norori, Carmen Paredes-Manrique, Nilton Custodio
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Behavioral Sciences
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Online Access:https://www.mdpi.com/2076-328X/15/2/207
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author Jonathan Adrián Zegarra-Valdivia
Brenda Chino
Kuripacha Tituana
Lina Zapata-Restrepo
María Martha Unaucho
Milton Lopez-Norori
Carmen Paredes-Manrique
Nilton Custodio
author_facet Jonathan Adrián Zegarra-Valdivia
Brenda Chino
Kuripacha Tituana
Lina Zapata-Restrepo
María Martha Unaucho
Milton Lopez-Norori
Carmen Paredes-Manrique
Nilton Custodio
author_sort Jonathan Adrián Zegarra-Valdivia
collection DOAJ
description The rising prevalence of dementia, particularly in low-income and developing countries, highlights the urgent need for effective cognitive screening tools. However, the existing tools often fail to address the unique needs of low-educated and illiterate populations, leading to diagnostic disparities. This review aimed to evaluate cognitive screening tests and domains employed globally to detect mild cognitive impairment (MCI) and dementia in low-educated and illiterate older adults. Following the PRISMA guidelines, Searches were performed in Web of Science, Scopus, and PubMed, targeting studies from January 2000 to 2023 involving adults over 45 years old. Of 1611 studies identified, 27 met the inclusion criteria and underwent pair review. The results revealed that most studies preferred adapting the existing tools to local languages over developing culturally tailored instruments. Twelve cognitive tests specifically designed for low-educated populations were identified, with the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) being the most utilized, despite their educational biases. Adjusting the cutoff points improved detection (e.g., MoCA: sensitivity 82.5%, specificity 82%). Notably, the Rowland Universal Dementia Assessment Scale (RUDAS) demonstrated superior performance for low-educated groups (sensitivity 89% and specificity 93%). The findings underscore the critical need for region-specific cognitive batteries that integrate functional assessments, ensuring equitable and accurate diagnosis across diverse educational backgrounds.
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spelling doaj-art-ee26a882b7e34829aa2c16a19b084fe72025-08-20T02:44:49ZengMDPI AGBehavioral Sciences2076-328X2025-02-0115220710.3390/bs15020207Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening ToolsJonathan Adrián Zegarra-Valdivia0Brenda Chino1Kuripacha Tituana2Lina Zapata-Restrepo3María Martha Unaucho4Milton Lopez-Norori5Carmen Paredes-Manrique6Nilton Custodio7Faculty of Health Sciences, Universidad Señor de Sipán, Km5 Road to Pimentel, Chiclayo 14001, PeruCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, 28040 Madrid, SpainGlobal Brain Health Institute (GBHI), University of California San Francisco, San Francisco, CA 90025, USAGlobal Brain Health Institute (GBHI), University of California San Francisco, San Francisco, CA 90025, USAGlobal Brain Health Institute (GBHI), University of California San Francisco, San Francisco, CA 90025, USAGlobal Brain Health Institute (GBHI), University of California San Francisco, San Francisco, CA 90025, USAFacultad de Psicologia, Universidad Tecnológica del Perú, Lima 15073, PeruInstituto Peruano de Neurociencias, Lima 15046, PeruThe rising prevalence of dementia, particularly in low-income and developing countries, highlights the urgent need for effective cognitive screening tools. However, the existing tools often fail to address the unique needs of low-educated and illiterate populations, leading to diagnostic disparities. This review aimed to evaluate cognitive screening tests and domains employed globally to detect mild cognitive impairment (MCI) and dementia in low-educated and illiterate older adults. Following the PRISMA guidelines, Searches were performed in Web of Science, Scopus, and PubMed, targeting studies from January 2000 to 2023 involving adults over 45 years old. Of 1611 studies identified, 27 met the inclusion criteria and underwent pair review. The results revealed that most studies preferred adapting the existing tools to local languages over developing culturally tailored instruments. Twelve cognitive tests specifically designed for low-educated populations were identified, with the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) being the most utilized, despite their educational biases. Adjusting the cutoff points improved detection (e.g., MoCA: sensitivity 82.5%, specificity 82%). Notably, the Rowland Universal Dementia Assessment Scale (RUDAS) demonstrated superior performance for low-educated groups (sensitivity 89% and specificity 93%). The findings underscore the critical need for region-specific cognitive batteries that integrate functional assessments, ensuring equitable and accurate diagnosis across diverse educational backgrounds.https://www.mdpi.com/2076-328X/15/2/207cognitive screening testilliteracylow educationolder adultsdementiamiddle cognitive impairment
spellingShingle Jonathan Adrián Zegarra-Valdivia
Brenda Chino
Kuripacha Tituana
Lina Zapata-Restrepo
María Martha Unaucho
Milton Lopez-Norori
Carmen Paredes-Manrique
Nilton Custodio
Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools
Behavioral Sciences
cognitive screening test
illiteracy
low education
older adults
dementia
middle cognitive impairment
title Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools
title_full Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools
title_fullStr Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools
title_full_unstemmed Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools
title_short Dementia and Mild Cognitive Impairment Identification in Illiterate and Low-Educated People: Systematic Review About the Use of Brief Cognitive Screening Tools
title_sort dementia and mild cognitive impairment identification in illiterate and low educated people systematic review about the use of brief cognitive screening tools
topic cognitive screening test
illiteracy
low education
older adults
dementia
middle cognitive impairment
url https://www.mdpi.com/2076-328X/15/2/207
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