Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system.

Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system.

To sustain the gonotrophic cycle, the Aedes aegypti mosquito must acquire a blood meal from a human or other vertebrate host. However, in the process of blood feeding, the mosquito may facilitate the transmission of several bloodborne viral pathogens (e.g., dengue, Zika, and chikungunya). The blood...

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Main Authors: Anthony J O'Donoghue, Chenxi Liu, Carter J Simington, Saira Montermoso, Elizabeth Moreno-Galvez, Mateus Sá M Serafim, Olive E Burata, Rachael M Lucero, James T Nguyen, Daniel Fong, Khanh Tran, Neomi Millan, Jamie M Gallimore, Kamille Parungao, Jonathan Fong, Brian M Suzuki, Zhenze Jiang, Jun Isoe, Alberto A Rascón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012555
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