18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures

Adrenal cortical carcinoma (ACC) is a rare aggressive endocrine tumor with poor prognosis. About 60% of ACC are functional tumors. Bilateral ACC is extremely rare, roughly 2%—10% of cases. Diagnosis and staging of ACC by imaging modalities are crucial for preoperative planning and prognostication. D...

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Main Authors: Apichaya Claimon, Ngoentra Tantranont, Torpong Claimon
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-07-01
Series:World Journal of Nuclear Medicine
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_86_19
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author Apichaya Claimon
Ngoentra Tantranont
Torpong Claimon
author_facet Apichaya Claimon
Ngoentra Tantranont
Torpong Claimon
author_sort Apichaya Claimon
collection DOAJ
description Adrenal cortical carcinoma (ACC) is a rare aggressive endocrine tumor with poor prognosis. About 60% of ACC are functional tumors. Bilateral ACC is extremely rare, roughly 2%—10% of cases. Diagnosis and staging of ACC by imaging modalities are crucial for preoperative planning and prognostication. Detection of hyperfunctional bilateral adrenocortical carcinoma by 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F- FDG PET/CT) has never been reported. Herein, we report a male patient who presented with Cushing's syndrome, type II diabetes mellitus due to Cushing's syndrome, and hypogonadism with biopsy confirmed left ACC. He underwent 18F-FDG PET/CT to evaluate the contralateral adrenal mass and to plan for laparoscopic adrenalectomy, which subsequently confirmed bilateral ACC. Furthermore,18F-FDG PET/CT was useful in staging, which revealed paraaortic lymph node and lung metastasis.
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institution OA Journals
issn 1450-1147
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language English
publishDate 2020-07-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series World Journal of Nuclear Medicine
spelling doaj-art-ee21e7fddd7440f78119c4fd813ae39a2025-08-20T02:04:33ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122020-07-01190330130510.4103/wjnm.WJNM_86_1918F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literaturesApichaya Claimon0Ngoentra Tantranont1Torpong Claimon2Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Radiology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, ThailandAdrenal cortical carcinoma (ACC) is a rare aggressive endocrine tumor with poor prognosis. About 60% of ACC are functional tumors. Bilateral ACC is extremely rare, roughly 2%—10% of cases. Diagnosis and staging of ACC by imaging modalities are crucial for preoperative planning and prognostication. Detection of hyperfunctional bilateral adrenocortical carcinoma by 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F- FDG PET/CT) has never been reported. Herein, we report a male patient who presented with Cushing's syndrome, type II diabetes mellitus due to Cushing's syndrome, and hypogonadism with biopsy confirmed left ACC. He underwent 18F-FDG PET/CT to evaluate the contralateral adrenal mass and to plan for laparoscopic adrenalectomy, which subsequently confirmed bilateral ACC. Furthermore,18F-FDG PET/CT was useful in staging, which revealed paraaortic lymph node and lung metastasis.http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_86_19 18f-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomographyadrenal cortical carcinomabilateralcushing's syndromelaparoscopic adrenalectomy
spellingShingle Apichaya Claimon
Ngoentra Tantranont
Torpong Claimon
18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
World Journal of Nuclear Medicine
18f-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography
adrenal cortical carcinoma
bilateral
cushing's syndrome
laparoscopic adrenalectomy
title 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
title_full 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
title_fullStr 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
title_full_unstemmed 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
title_short 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
title_sort 18f fluoro 2 deoxy d glucose positron emission tomography computed tomography for preoperative planning in a rare case of hyperfunctional bilateral adrenocortical carcinoma and review of literatures
topic 18f-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography
adrenal cortical carcinoma
bilateral
cushing's syndrome
laparoscopic adrenalectomy
url http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_86_19
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