CRISPRa-Mediated Triple-Gene Activation of <i>ARO10</i>, <i>ARO80,</i> and <i>ADH2</i> for Enhancing 2-Phenylethanol Biosynthesis via the Ehrlich Pathway in <i>Saccharomyces cerevisiae</i>

CRISPRa-Mediated Triple-Gene Activation of <i>ARO10</i>, <i>ARO80,</i> and <i>ADH2</i> for Enhancing 2-Phenylethanol Biosynthesis via the Ehrlich Pathway in <i>Saccharomyces cerevisiae</i>

2-phenylethanol (2-PE), a rose-like fragrance compound, is widely used in the food industry. Conventional chemical synthesis of 2-PE faces significant challenges due to environmental concerns and consumer preferences; thus, using <i>Saccharomyces cerevisiae</i> (<i>S. cerevisiae<...

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Bibliographic Details
Main Authors: Zijing Zhu, Shuaihu Fang, Pingping Huang, Dianqiang Luo, Xiaobao Qi
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Fermentation
Subjects:
2-phenylethanol
<i>Saccharomyces cerevisiae</i>
CRISPRa
Ehrlich pathway
Online Access:https://www.mdpi.com/2311-5637/11/6/345
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