Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers
Aim. Smoking is a major risk factor for diabetes mellitus, mainly due to decreased insulin secretion and increased insulin resistance. However, there has been little research on the effects of smoking cessation period on changes in insulin resistance. In this study, we investigated the relationships...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2017/6074760 |
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| _version_ | 1832563392111443968 |
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| author | Ko-Woon Kim Sung-Goo Kang Sang-Wook Song Na-Rae Kim Jun-Seung Rho Yun-Ah Lee |
| author_facet | Ko-Woon Kim Sung-Goo Kang Sang-Wook Song Na-Rae Kim Jun-Seung Rho Yun-Ah Lee |
| author_sort | Ko-Woon Kim |
| collection | DOAJ |
| description | Aim. Smoking is a major risk factor for diabetes mellitus, mainly due to decreased insulin secretion and increased insulin resistance. However, there has been little research on the effects of smoking cessation period on changes in insulin resistance. In this study, we investigated the relationships between the length of time since smoking cessation period and insulin resistance in asymptomatic Korean male ex-smokers. Methods. A total of 851 male adults were included in this study. We considered several factors that can affect insulin resistance, and through multiple linear regression analysis, we assessed the effect the length of time since smoking cessation on insulin resistance in ex-smokers. Insulin resistance was represented as the insulin resistance index estimated by homeostasis model assessment. Results. HOMA-IR values showed a statistically significant negative correlation with the length of time since smoking cessation (p=0.009) in ex-smokers. After performing multiple linear regression analysis using factors that could potentially influence insulin resistance, we found that waist circumference (p=0.026) and the length of time since smoking cessation (p=0.039) were independent predictors of HOMA-IR in asymptomatic male ex-smokers. Conclusion. The longer the smoking cessation period, the more the insulin resistance tended to decrease in asymptomatic Korean male ex-smokers. |
| format | Article |
| id | doaj-art-ee1a6853efce412db03e4cac39a96727 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-ee1a6853efce412db03e4cac39a967272025-02-03T01:20:25ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/60747606074760Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-SmokersKo-Woon Kim0Sung-Goo Kang1Sang-Wook Song2Na-Rae Kim3Jun-Seung Rho4Yun-Ah Lee5Department of Family Medicine, College of Medicine, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of KoreaDepartment of Family Medicine, College of Medicine, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of KoreaDepartment of Family Medicine, College of Medicine, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of KoreaDepartment of Family Medicine, College of Medicine, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of KoreaDepartment of Family Medicine, College of Medicine, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of KoreaDepartment of Family Medicine, College of Medicine, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of KoreaAim. Smoking is a major risk factor for diabetes mellitus, mainly due to decreased insulin secretion and increased insulin resistance. However, there has been little research on the effects of smoking cessation period on changes in insulin resistance. In this study, we investigated the relationships between the length of time since smoking cessation period and insulin resistance in asymptomatic Korean male ex-smokers. Methods. A total of 851 male adults were included in this study. We considered several factors that can affect insulin resistance, and through multiple linear regression analysis, we assessed the effect the length of time since smoking cessation on insulin resistance in ex-smokers. Insulin resistance was represented as the insulin resistance index estimated by homeostasis model assessment. Results. HOMA-IR values showed a statistically significant negative correlation with the length of time since smoking cessation (p=0.009) in ex-smokers. After performing multiple linear regression analysis using factors that could potentially influence insulin resistance, we found that waist circumference (p=0.026) and the length of time since smoking cessation (p=0.039) were independent predictors of HOMA-IR in asymptomatic male ex-smokers. Conclusion. The longer the smoking cessation period, the more the insulin resistance tended to decrease in asymptomatic Korean male ex-smokers.http://dx.doi.org/10.1155/2017/6074760 |
| spellingShingle | Ko-Woon Kim Sung-Goo Kang Sang-Wook Song Na-Rae Kim Jun-Seung Rho Yun-Ah Lee Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers Journal of Diabetes Research |
| title | Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers |
| title_full | Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers |
| title_fullStr | Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers |
| title_full_unstemmed | Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers |
| title_short | Association between the Time of Length since Smoking Cessation and Insulin Resistance in Asymptomatic Korean Male Ex-Smokers |
| title_sort | association between the time of length since smoking cessation and insulin resistance in asymptomatic korean male ex smokers |
| url | http://dx.doi.org/10.1155/2017/6074760 |
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