Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution

Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution

Abstract Neurodegenerative diseases and serious mental illnesses often exhibit overlapping characteristics, highlighting the potential for shared underlying mechanisms. To facilitate a deeper understanding of these diseases and pave the way for more effective treatments, we have generated a populati...

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Main Authors: John F. Fullard, Prashant NM, Donghoon Lee, Deepika Mathur, Karen Therrien, Aram Hong, Clara Casey, Zhiping Shao, Marcela Alvia, Stathis Argyriou, Tereza Clarence, David Burstein, Sanan Venkatesh, Pavan K. Auluck, Lisa L. Barnes, David A. Bennett, Stefano Marenco, PsychAD Consortium, Kiran Girdhar, Vahram Haroutunian, Gabriel E. Hoffman, Georgios Voloudakis, Jaroslav Bendl, Panos Roussos
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04687-5
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