Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India

Introduction: The overall survival in pediatric acute lymphoblastic leukemia (ALL) ranges from 45 to 81% in India. Aggressive chemotherapy protocols like MCP841 have improved the outcome and it can be delivered with minimal supportive care. This study retrospectively analyses the clinical...

Full description

Saved in:
Bibliographic Details
Main Authors: Swarnabindu Banerjee, Sanjukta Saha, Dibyendu Raychaudhuri, Mihir Sarkar, Kalpana Datta
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2024-12-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788703
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850162388124303360
author Swarnabindu Banerjee
Sanjukta Saha
Dibyendu Raychaudhuri
Mihir Sarkar
Kalpana Datta
author_facet Swarnabindu Banerjee
Sanjukta Saha
Dibyendu Raychaudhuri
Mihir Sarkar
Kalpana Datta
author_sort Swarnabindu Banerjee
collection DOAJ
description Introduction: The overall survival in pediatric acute lymphoblastic leukemia (ALL) ranges from 45 to 81% in India. Aggressive chemotherapy protocols like MCP841 have improved the outcome and it can be delivered with minimal supportive care. This study retrospectively analyses the clinical profile and overall survival of patients treated by this protocol.
format Article
id doaj-art-ee0cc3693cd6477f8bd5982999b2b6b9
institution OA Journals
issn 0971-5851
0975-2129
language English
publishDate 2024-12-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-ee0cc3693cd6477f8bd5982999b2b6b92025-08-20T02:22:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292024-12-01450650951410.1055/s-0044-1788703Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern IndiaSwarnabindu Banerjee0Sanjukta Saha1Dibyendu Raychaudhuri2https://orcid.org/0000-0002-1785-1026Mihir Sarkar3Kalpana Datta4Department of Medical Oncology, Medical College and Hospital, Kolkata, IndiaDepartment of Paediatrics, Medical College and hospital, Kolkata, IndiaDepartment of Paediatrics, Medical College and hospital, Kolkata, IndiaDepartment of Paediatrics, Medical College and hospital, Kolkata, IndiaDepartment of Paediatrics, Medical College and hospital, Kolkata, India Introduction: The overall survival in pediatric acute lymphoblastic leukemia (ALL) ranges from 45 to 81% in India. Aggressive chemotherapy protocols like MCP841 have improved the outcome and it can be delivered with minimal supportive care. This study retrospectively analyses the clinical profile and overall survival of patients treated by this protocol.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788703acute lymphoblastic leukemiahigh-dose cytarabineMCP841 protocolretrospective studysurvival analysis
spellingShingle Swarnabindu Banerjee
Sanjukta Saha
Dibyendu Raychaudhuri
Mihir Sarkar
Kalpana Datta
Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India
Indian Journal of Medical and Paediatric Oncology
acute lymphoblastic leukemia
high-dose cytarabine
MCP841 protocol
retrospective study
survival analysis
title Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India
title_full Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India
title_fullStr Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India
title_full_unstemmed Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India
title_short Clinical Profile, Toxicities, and Survival Outcome of MCP841 in Pediatric Acute Lymphoblastic Leukemia in Current Era: A Retrospective Study from Eastern India
title_sort clinical profile toxicities and survival outcome of mcp841 in pediatric acute lymphoblastic leukemia in current era a retrospective study from eastern india
topic acute lymphoblastic leukemia
high-dose cytarabine
MCP841 protocol
retrospective study
survival analysis
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788703
work_keys_str_mv AT swarnabindubanerjee clinicalprofiletoxicitiesandsurvivaloutcomeofmcp841inpediatricacutelymphoblasticleukemiaincurrenteraaretrospectivestudyfromeasternindia
AT sanjuktasaha clinicalprofiletoxicitiesandsurvivaloutcomeofmcp841inpediatricacutelymphoblasticleukemiaincurrenteraaretrospectivestudyfromeasternindia
AT dibyenduraychaudhuri clinicalprofiletoxicitiesandsurvivaloutcomeofmcp841inpediatricacutelymphoblasticleukemiaincurrenteraaretrospectivestudyfromeasternindia
AT mihirsarkar clinicalprofiletoxicitiesandsurvivaloutcomeofmcp841inpediatricacutelymphoblasticleukemiaincurrenteraaretrospectivestudyfromeasternindia
AT kalpanadatta clinicalprofiletoxicitiesandsurvivaloutcomeofmcp841inpediatricacutelymphoblasticleukemiaincurrenteraaretrospectivestudyfromeasternindia