Imaging and MR Spectroscopy in Papillary Craniopharyngioma

Sellar-suprasellar masses exhibit a diverse range of differential diagnoses and it is feasible to establish a preliminary diagnosis before surgery by evaluating conventional CT scans and contrast-enhanced MRI results. Nevertheless, certain cases may present with inconclusive findings, making it cha...

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Main Authors: Ashima Mahajan, Bheru Dan Charan, Sushant Agarwal, Vinay Goel, Leve Joseph Devarajan Sebastian, Vaishali Suri, Ashish Suri, Ajay Garg
Format: Article
Language:English
Published: Vilnius University Press 2024-05-01
Series:Acta Medica Lituanica
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Online Access:https://www.journals.vu.lt/AML/article/view/33771
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author Ashima Mahajan
Bheru Dan Charan
Sushant Agarwal
Vinay Goel
Leve Joseph Devarajan Sebastian
Vaishali Suri
Ashish Suri
Ajay Garg
author_facet Ashima Mahajan
Bheru Dan Charan
Sushant Agarwal
Vinay Goel
Leve Joseph Devarajan Sebastian
Vaishali Suri
Ashish Suri
Ajay Garg
author_sort Ashima Mahajan
collection DOAJ
description Sellar-suprasellar masses exhibit a diverse range of differential diagnoses and it is feasible to establish a preliminary diagnosis before surgery by evaluating conventional CT scans and contrast-enhanced MRI results. Nevertheless, certain cases may present with inconclusive findings, making it challenging to anticipate the underlying tissue composition accurately through imaging alone. Researchers have explored the application of Proton MR spectroscopy in analyzing suprasellar tumors, and their investigations have revealed that it can complement traditional MRI by enhancing the accuracy of preoperative diagnoses. In this context, we report three biopsy-proven cases of suprasellar papillary craniopharyngioma where the MRS spectra derived from the solid component exhibited noticeable lipid peaks alongside reduced levels of choline and NAA. These findings played a pivotal role in facilitating the correct preoperative identification of papillary craniopharyngioma.
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institution Kabale University
issn 1392-0138
2029-4174
language English
publishDate 2024-05-01
publisher Vilnius University Press
record_format Article
series Acta Medica Lituanica
spelling doaj-art-ee05cf2b0e2b43008d5706718d9afd7a2025-01-20T18:07:59ZengVilnius University PressActa Medica Lituanica1392-01382029-41742024-05-0131110.15388/Amed.2024.31.1.10Imaging and MR Spectroscopy in Papillary CraniopharyngiomaAshima Mahajan0Bheru Dan Charan1Sushant Agarwal2Vinay Goel3Leve Joseph Devarajan Sebastian4Vaishali Suri5Ashish Suri6Ajay Garg7Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neurosurgery, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India Sellar-suprasellar masses exhibit a diverse range of differential diagnoses and it is feasible to establish a preliminary diagnosis before surgery by evaluating conventional CT scans and contrast-enhanced MRI results. Nevertheless, certain cases may present with inconclusive findings, making it challenging to anticipate the underlying tissue composition accurately through imaging alone. Researchers have explored the application of Proton MR spectroscopy in analyzing suprasellar tumors, and their investigations have revealed that it can complement traditional MRI by enhancing the accuracy of preoperative diagnoses. In this context, we report three biopsy-proven cases of suprasellar papillary craniopharyngioma where the MRS spectra derived from the solid component exhibited noticeable lipid peaks alongside reduced levels of choline and NAA. These findings played a pivotal role in facilitating the correct preoperative identification of papillary craniopharyngioma. https://www.journals.vu.lt/AML/article/view/33771CraniopharyngiomaSpectroscopySuprasellar
spellingShingle Ashima Mahajan
Bheru Dan Charan
Sushant Agarwal
Vinay Goel
Leve Joseph Devarajan Sebastian
Vaishali Suri
Ashish Suri
Ajay Garg
Imaging and MR Spectroscopy in Papillary Craniopharyngioma
Acta Medica Lituanica
Craniopharyngioma
Spectroscopy
Suprasellar
title Imaging and MR Spectroscopy in Papillary Craniopharyngioma
title_full Imaging and MR Spectroscopy in Papillary Craniopharyngioma
title_fullStr Imaging and MR Spectroscopy in Papillary Craniopharyngioma
title_full_unstemmed Imaging and MR Spectroscopy in Papillary Craniopharyngioma
title_short Imaging and MR Spectroscopy in Papillary Craniopharyngioma
title_sort imaging and mr spectroscopy in papillary craniopharyngioma
topic Craniopharyngioma
Spectroscopy
Suprasellar
url https://www.journals.vu.lt/AML/article/view/33771
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