Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunc...

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Main Authors: Genevieve Walls, Lisa Noonan, Elizabeth Wilson, David Holland, Simon Briggs
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2013/508908
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author Genevieve Walls
Lisa Noonan
Elizabeth Wilson
David Holland
Simon Briggs
author_facet Genevieve Walls
Lisa Noonan
Elizabeth Wilson
David Holland
Simon Briggs
author_sort Genevieve Walls
collection DOAJ
description Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunct to standard surgical and medical treatment. Also presented is a literature review on the use of polyhexamethylene biguanide for this indication. The authors recommend that this safe and well-tolerated compound be considered as part of the treatment for fungal osteomyelitis.
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publishDate 2013-01-01
publisher Wiley
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-ee039b7745c247f0a899174d91acff7e2025-08-20T02:21:42ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-0124210911210.1155/2013/508908Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal OsteomyelitisGenevieve Walls0Lisa Noonan1Elizabeth Wilson2David Holland3Simon Briggs4Department of Infectious Diseases, Auckland City Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Auckland City Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Starship Children’s Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Middlemore Hospital, Auckland, New ZealandDepartment of Infectious Diseases, Auckland City Hospital, Auckland, New ZealandFungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene biguanide, was used successfully as an adjunct to standard surgical and medical treatment. Also presented is a literature review on the use of polyhexamethylene biguanide for this indication. The authors recommend that this safe and well-tolerated compound be considered as part of the treatment for fungal osteomyelitis.http://dx.doi.org/10.1155/2013/508908
spellingShingle Genevieve Walls
Lisa Noonan
Elizabeth Wilson
David Holland
Simon Briggs
Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
Canadian Journal of Infectious Diseases and Medical Microbiology
title Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_full Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_fullStr Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_full_unstemmed Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_short Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis
title_sort successful use of locally applied polyhexamethylene biguanide as an adjunct to the treatment of fungal osteomyelitis
url http://dx.doi.org/10.1155/2013/508908
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AT elizabethwilson successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis
AT davidholland successfuluseoflocallyappliedpolyhexamethylenebiguanideasanadjuncttothetreatmentoffungalosteomyelitis
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