A comprehensive review of the pathogenic mechanisms of Pseudomonas aeruginosa: synergistic effects of virulence factors, quorum sensing, and biofilm formation

A comprehensive review of the pathogenic mechanisms of Pseudomonas aeruginosa: synergistic effects of virulence factors, quorum sensing, and biofilm formation

Pseudomonas aeruginosa (P. aeruginosa) is a ubiquitous opportunistic pathogen and a major cause of nosocomial infections worldwide. It can provoke a spectrum of clinical manifestations-ranging from postoperative wound infections, pressure ulcers, abscesses, and otitis media to life-threatening bacte...

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Bibliographic Details
Main Authors: Xindan Zhang, Duo Zhang, Di Zhou, Shuai Zheng, Shuang Li, Qinlong Hou, Gen Li, Huiming Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
virulence factors
quorum sensing
biofilm
immune evasion
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1619626/full
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