The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil
ABSTRACT Objective The aim of this study was to translate and adapt the Newcastle Paediatric Mitochondrial Disease Scale (NPMDS) to Portuguese for use in Brazil. Methods The scale was applied in 20 pediatric patients with mitochondrial disease, in three groups: myopathy (n = 4); Leigh syndrome (...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001100909&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850165554736791552 |
|---|---|
| author | Gabriela Palhares Campolina-Sampaio Laura Maria de Lima Belizário Facury Lasmar Beatriz Silva Vilela Ribeiro Juliana Gurgel Giannetti |
| author_facet | Gabriela Palhares Campolina-Sampaio Laura Maria de Lima Belizário Facury Lasmar Beatriz Silva Vilela Ribeiro Juliana Gurgel Giannetti |
| author_sort | Gabriela Palhares Campolina-Sampaio |
| collection | DOAJ |
| description | ABSTRACT Objective The aim of this study was to translate and adapt the Newcastle Paediatric Mitochondrial Disease Scale (NPMDS) to Portuguese for use in Brazil. Methods The scale was applied in 20 pediatric patients with mitochondrial disease, in three groups: myopathy (n = 4); Leigh syndrome (n = 8); and encephalomyopathy (n = 8). Scores were obtained for the various dimensions of the NPMDS, and comparisons were drawn between the groups. Results There was a statistically significant difference between the myopathy group and the Leigh syndrome group (p = 0.0085), as well as between the myopathy and encephalomyopathy groups (p = 0.01). Conclusions The translation of the NPMDS, and its adaptation to the socioeconomic and cultural conditions in Brazil, make the NPMDS score useful as an additional parameter in the evaluation and monitoring of pediatric patients with MD in Brazil. |
| format | Article |
| id | doaj-art-edfd006dc0874bbdbd983b4ffd96c718 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-edfd006dc0874bbdbd983b4ffd96c7182025-08-20T02:21:42ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-4227741190991310.1590/0004-282x20160137S0004-282X2016001100909The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in BrazilGabriela Palhares Campolina-SampaioLaura Maria de Lima Belizário Facury LasmarBeatriz Silva Vilela RibeiroJuliana Gurgel GiannettiABSTRACT Objective The aim of this study was to translate and adapt the Newcastle Paediatric Mitochondrial Disease Scale (NPMDS) to Portuguese for use in Brazil. Methods The scale was applied in 20 pediatric patients with mitochondrial disease, in three groups: myopathy (n = 4); Leigh syndrome (n = 8); and encephalomyopathy (n = 8). Scores were obtained for the various dimensions of the NPMDS, and comparisons were drawn between the groups. Results There was a statistically significant difference between the myopathy group and the Leigh syndrome group (p = 0.0085), as well as between the myopathy and encephalomyopathy groups (p = 0.01). Conclusions The translation of the NPMDS, and its adaptation to the socioeconomic and cultural conditions in Brazil, make the NPMDS score useful as an additional parameter in the evaluation and monitoring of pediatric patients with MD in Brazil.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001100909&lng=en&tlng=enNewcastle diseasemitochondrial diseases, mitochondrial myopathiesmitochondrial encephalomyopathiesLeigh disease |
| spellingShingle | Gabriela Palhares Campolina-Sampaio Laura Maria de Lima Belizário Facury Lasmar Beatriz Silva Vilela Ribeiro Juliana Gurgel Giannetti The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil Arquivos de Neuro-Psiquiatria Newcastle disease mitochondrial diseases, mitochondrial myopathies mitochondrial encephalomyopathies Leigh disease |
| title | The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil |
| title_full | The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil |
| title_fullStr | The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil |
| title_full_unstemmed | The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil |
| title_short | The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil |
| title_sort | newcastle pediatric mitochondrial disease scale translation and cultural adaptation for use in brazil |
| topic | Newcastle disease mitochondrial diseases, mitochondrial myopathies mitochondrial encephalomyopathies Leigh disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001100909&lng=en&tlng=en |
| work_keys_str_mv | AT gabrielapalharescampolinasampaio thenewcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT lauramariadelimabelizariofacurylasmar thenewcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT beatrizsilvavilelaribeiro thenewcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT julianagurgelgiannetti thenewcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT gabrielapalharescampolinasampaio newcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT lauramariadelimabelizariofacurylasmar newcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT beatrizsilvavilelaribeiro newcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil AT julianagurgelgiannetti newcastlepediatricmitochondrialdiseasescaletranslationandculturaladaptationforuseinbrazil |