Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis
Abstract The infectious and inflammatory process of the periodontal tissues can contribute to hyperglycemia in patients with diabetes. Objective The objective of this study was to evaluate the effect of non-surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellit...
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University of São Paulo
2025-07-01
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| Series: | Journal of Applied Oral Science |
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| author | Rafael Paschoal ESTEVES LIMA Karolina Skarlet Silva VIANA Pierre Geraldo Braz da SILVA JUNIOR Luís Otávio Miranda COTA Fernando Oliveira COSTA |
| author_facet | Rafael Paschoal ESTEVES LIMA Karolina Skarlet Silva VIANA Pierre Geraldo Braz da SILVA JUNIOR Luís Otávio Miranda COTA Fernando Oliveira COSTA |
| author_sort | Rafael Paschoal ESTEVES LIMA |
| collection | DOAJ |
| description | Abstract The infectious and inflammatory process of the periodontal tissues can contribute to hyperglycemia in patients with diabetes. Objective The objective of this study was to evaluate the effect of non-surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus. Methodology In this clinical trial with two months of follow-up, 31 participants were included, with 15 having adequate glycemic control and 16 inadequate glycemic control. The participants underwent non-surgical periodontal therapy. Biological, social, and behavioral variables were collected. Periodontal clinical examination was performed at baseline and two months after the intervention. Laboratory tests to assess serum levels of glycated hemoglobin, fasting glucose, and C-reactive protein were requested for all participants at baseline and two months after periodontal treatment. Results The difference in glycated hemoglobin levels between baseline and two months after non-surgical periodontal therapy was statistically significant in the total sample (p=0.045) and in the group of individuals with adequate glycemic control (p=0.016). No significant difference was observed in glycated hemoglobin levels in the group of individuals with inadequate glycemic control. No significant variation was observed in fasting glucose and C-reactive protein levels after treatment in the studied sample. A reduction in probing depth, gingival inflammation, and gain in clinical attachment was observed in the total sample and in both groups according to glycemic control. Conclusion Periodontal intervention may contribute to improved glycemic control in individuals with type 2 diabetes mellitus and periodontitis (Brazilian Clinical Trials Registry RBR-9fvwk4m). |
| format | Article |
| id | doaj-art-eddb9aebaaec410eaa2780378759cbfe |
| institution | Kabale University |
| issn | 1678-7765 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj-art-eddb9aebaaec410eaa2780378759cbfe2025-08-20T03:30:24ZengUniversity of São PauloJournal of Applied Oral Science1678-77652025-07-013310.1590/1678-7757-2025-0121Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitisRafael Paschoal ESTEVES LIMAhttps://orcid.org/0000-0003-4343-3845Karolina Skarlet Silva VIANAhttps://orcid.org/0000-0001-6467-1434Pierre Geraldo Braz da SILVA JUNIORhttps://orcid.org/0000-0002-9140-8997Luís Otávio Miranda COTAhttps://orcid.org/0000-0003-1517-5842Fernando Oliveira COSTAhttps://orcid.org/0000-0003-4104-8353Abstract The infectious and inflammatory process of the periodontal tissues can contribute to hyperglycemia in patients with diabetes. Objective The objective of this study was to evaluate the effect of non-surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus. Methodology In this clinical trial with two months of follow-up, 31 participants were included, with 15 having adequate glycemic control and 16 inadequate glycemic control. The participants underwent non-surgical periodontal therapy. Biological, social, and behavioral variables were collected. Periodontal clinical examination was performed at baseline and two months after the intervention. Laboratory tests to assess serum levels of glycated hemoglobin, fasting glucose, and C-reactive protein were requested for all participants at baseline and two months after periodontal treatment. Results The difference in glycated hemoglobin levels between baseline and two months after non-surgical periodontal therapy was statistically significant in the total sample (p=0.045) and in the group of individuals with adequate glycemic control (p=0.016). No significant difference was observed in glycated hemoglobin levels in the group of individuals with inadequate glycemic control. No significant variation was observed in fasting glucose and C-reactive protein levels after treatment in the studied sample. A reduction in probing depth, gingival inflammation, and gain in clinical attachment was observed in the total sample and in both groups according to glycemic control. Conclusion Periodontal intervention may contribute to improved glycemic control in individuals with type 2 diabetes mellitus and periodontitis (Brazilian Clinical Trials Registry RBR-9fvwk4m).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572025000100434&lng=en&tlng=enGlycemic controlDental scalingDiabetes mellitus, type 2Periodontitis |
| spellingShingle | Rafael Paschoal ESTEVES LIMA Karolina Skarlet Silva VIANA Pierre Geraldo Braz da SILVA JUNIOR Luís Otávio Miranda COTA Fernando Oliveira COSTA Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis Journal of Applied Oral Science Glycemic control Dental scaling Diabetes mellitus, type 2 Periodontitis |
| title | Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis |
| title_full | Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis |
| title_fullStr | Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis |
| title_full_unstemmed | Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis |
| title_short | Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis |
| title_sort | impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis |
| topic | Glycemic control Dental scaling Diabetes mellitus, type 2 Periodontitis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572025000100434&lng=en&tlng=en |
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