Extrahepatic disease clusters and mortality in people with steatotic liver diseases: a prospective analysis of 64,749 females and 113,587 males in the UK Biobank

Extrahepatic disease clusters and mortality in people with steatotic liver diseases: a prospective analysis of 64,749 females and 113,587 males in the UK Biobank

Abstract Background Steatotic liver disease (SLD) is the most prevalent chronic liver disease worldwide and linked to various liver and extrahepatic diseases. However, the clustering of extrahepatic conditions and their impact on mortality in individuals with SLD remain poorly understood. Methods We...

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Bibliographic Details
Main Authors: Qi Feng, Chioma N. Izzi-Engbeaya, Thomas Beaney, Alexander G. Smith, Pinelopi Manousou, Mark Woodward
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Steatotic liver disease
Multimorbidity
Disease cluster
Mortality
Latent class analysis
Sex difference
Online Access:https://doi.org/10.1186/s12916-025-04288-4
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