Research Progress on Low Specific Activity 99Mo-99mTc Generators

The radioisotope 99mTc is widely used in the clinical diagnostic field of nuclear medicine,which is mainly obtained by β-decay of the parent nuclide 99Mo in 99Mo-99mTc generator. Due to the shutdown of multiple reactors producing 99Mo,the stable supply of fission 99Mo is threatened. In addition,the...

Full description

Saved in:
Bibliographic Details
Main Authors: Rui YANG, Jun xiang SHU, Xu LUO
Format: Article
Language:zho
Published: Editorial Board of Journal of Isotopes 2025-02-01
Series:Journal of Isotopes
Subjects:
Online Access:https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.113
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832589877878718464
author Rui YANG
Jun xiang SHU
Xu LUO
author_facet Rui YANG
Jun xiang SHU
Xu LUO
author_sort Rui YANG
collection DOAJ
description The radioisotope 99mTc is widely used in the clinical diagnostic field of nuclear medicine,which is mainly obtained by β-decay of the parent nuclide 99Mo in 99Mo-99mTc generator. Due to the shutdown of multiple reactors producing 99Mo,the stable supply of fission 99Mo is threatened. In addition,the production of fission 99Mo may lead to nuclear proliferation. As a result,the raw materials for the fission-99Mo-99mTc generators decreased. Therefore,reactor irradiation and accelerator-based 99Mo production technology have attracted the attention of various countries. New 99Mo-99mTc generators are also constantly being developed. This paper briefly discusses the current production status of low specific activity 99Mo in China and the separation methods of low specific activity 99Mo-99mTc. Furthermore,the 99Mo-99mTc generator is also discussed,which is expected to provide some reference for the development of new 99Mo-99mTc generators in the future.
format Article
id doaj-art-edcfbe7d09304ba6b1bb6b328761ece4
institution Kabale University
issn 1000-7512
language zho
publishDate 2025-02-01
publisher Editorial Board of Journal of Isotopes
record_format Article
series Journal of Isotopes
spelling doaj-art-edcfbe7d09304ba6b1bb6b328761ece42025-01-24T06:37:08ZzhoEditorial Board of Journal of IsotopesJournal of Isotopes1000-75122025-02-01381485510.7538/tws.2024.youxian.113202412113Research Progress on Low Specific Activity 99Mo-99mTc GeneratorsRui YANG0Jun xiang SHU1Xu LUO2Chengdu Gaotong Isotope Co., Ltd.(CNNC), Chengdu 610041, ChinaChengdu Gaotong Isotope Co., Ltd.(CNNC), Chengdu 610041, ChinaChengdu Gaotong Isotope Co., Ltd.(CNNC), Chengdu 610041, ChinaThe radioisotope 99mTc is widely used in the clinical diagnostic field of nuclear medicine,which is mainly obtained by β-decay of the parent nuclide 99Mo in 99Mo-99mTc generator. Due to the shutdown of multiple reactors producing 99Mo,the stable supply of fission 99Mo is threatened. In addition,the production of fission 99Mo may lead to nuclear proliferation. As a result,the raw materials for the fission-99Mo-99mTc generators decreased. Therefore,reactor irradiation and accelerator-based 99Mo production technology have attracted the attention of various countries. New 99Mo-99mTc generators are also constantly being developed. This paper briefly discusses the current production status of low specific activity 99Mo in China and the separation methods of low specific activity 99Mo-99mTc. Furthermore,the 99Mo-99mTc generator is also discussed,which is expected to provide some reference for the development of new 99Mo-99mTc generators in the future.https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.113low specific activityproduction of 99mo99mo-99mtc generator
spellingShingle Rui YANG
Jun xiang SHU
Xu LUO
Research Progress on Low Specific Activity 99Mo-99mTc Generators
Journal of Isotopes
low specific activity
production of 99mo
99mo-99mtc generator
title Research Progress on Low Specific Activity 99Mo-99mTc Generators
title_full Research Progress on Low Specific Activity 99Mo-99mTc Generators
title_fullStr Research Progress on Low Specific Activity 99Mo-99mTc Generators
title_full_unstemmed Research Progress on Low Specific Activity 99Mo-99mTc Generators
title_short Research Progress on Low Specific Activity 99Mo-99mTc Generators
title_sort research progress on low specific activity 99mo 99mtc generators
topic low specific activity
production of 99mo
99mo-99mtc generator
url https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.113
work_keys_str_mv AT ruiyang researchprogressonlowspecificactivity99mo99mtcgenerators
AT junxiangshu researchprogressonlowspecificactivity99mo99mtcgenerators
AT xuluo researchprogressonlowspecificactivity99mo99mtcgenerators