High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats
This study was carried out to comparatively assess the potentiating effects of majorly consumed brands of energy drinks (red bull, power horse and bullet) on several metabolic stress indicators. The study comprised four groups. Group I which served as control had normal feed and water only, group II...
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| Format: | Article |
| Language: | English |
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Hammer Head Production Limited
2018-09-01
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| Series: | Sokoto Journal of Medical Laboratory Science |
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| Online Access: | https://sokjmls.com.ng/index.php/SJMLS/article/view/251 |
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| author | Kweki, G.R. , Ichipi-Ifukor, P.C.* , Asagba, S.O. |
| author_facet | Kweki, G.R. , Ichipi-Ifukor, P.C.* , Asagba, S.O. |
| author_sort | Kweki, G.R. , Ichipi-Ifukor, P.C.* , Asagba, S.O. |
| collection | DOAJ |
| description | This study was carried out to comparatively assess the potentiating effects of majorly consumed brands of energy drinks (red bull, power horse and bullet) on several metabolic stress indicators. The study comprised four groups. Group I which served as control had normal feed and water only, group II-IV was given normal feed and 0.8ml/Kg body weight of Red Bull, Bullet and Power Horse energy
drinks respectively for 42 days. Animals were sacrificed on the 43 rd day following an overnight fast and samples collected for tissue and plasma assay of biochemical markers. There was significant rise (p<0.05) in plasma and tissue ALT, AST, plasma ALP activities in rats administered all three brands of energy drinks, while plasma creatinine and urea only increased in rats that consumed Power Horse compared to controls. Changes in tissue (brain, kidney, heart and liver) lipid peroxidation indicates significant (p<0.05) increase relative to controls. Tissue oxidative enzymes (AO and SO) were significantly increased and depleted respectively compared to controls. The uncontrolled consumption of energy drinks is overtly unsafe as it has the capability of inducing metabolic stress via the
induction and depletion of several tissue and plasma metabolic stress markers. |
| format | Article |
| id | doaj-art-edce11d35e91442d893e97e722531145 |
| institution | Kabale University |
| issn | 2536-7153 |
| language | English |
| publishDate | 2018-09-01 |
| publisher | Hammer Head Production Limited |
| record_format | Article |
| series | Sokoto Journal of Medical Laboratory Science |
| spelling | doaj-art-edce11d35e91442d893e97e7225311452025-08-20T03:42:45ZengHammer Head Production LimitedSokoto Journal of Medical Laboratory Science2536-71532018-09-0133251High Caffeine- Containing Energy Drink- Induced Metabolic Stress in RatsKweki, G.R. , Ichipi-Ifukor, P.C.* , Asagba, S.O.This study was carried out to comparatively assess the potentiating effects of majorly consumed brands of energy drinks (red bull, power horse and bullet) on several metabolic stress indicators. The study comprised four groups. Group I which served as control had normal feed and water only, group II-IV was given normal feed and 0.8ml/Kg body weight of Red Bull, Bullet and Power Horse energy drinks respectively for 42 days. Animals were sacrificed on the 43 rd day following an overnight fast and samples collected for tissue and plasma assay of biochemical markers. There was significant rise (p<0.05) in plasma and tissue ALT, AST, plasma ALP activities in rats administered all three brands of energy drinks, while plasma creatinine and urea only increased in rats that consumed Power Horse compared to controls. Changes in tissue (brain, kidney, heart and liver) lipid peroxidation indicates significant (p<0.05) increase relative to controls. Tissue oxidative enzymes (AO and SO) were significantly increased and depleted respectively compared to controls. The uncontrolled consumption of energy drinks is overtly unsafe as it has the capability of inducing metabolic stress via the induction and depletion of several tissue and plasma metabolic stress markers.https://sokjmls.com.ng/index.php/SJMLS/article/view/251energy drink, caffeine and metabolic stress |
| spellingShingle | Kweki, G.R. , Ichipi-Ifukor, P.C.* , Asagba, S.O. High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats Sokoto Journal of Medical Laboratory Science energy drink, caffeine and metabolic stress |
| title | High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats |
| title_full | High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats |
| title_fullStr | High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats |
| title_full_unstemmed | High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats |
| title_short | High Caffeine- Containing Energy Drink- Induced Metabolic Stress in Rats |
| title_sort | high caffeine containing energy drink induced metabolic stress in rats |
| topic | energy drink, caffeine and metabolic stress |
| url | https://sokjmls.com.ng/index.php/SJMLS/article/view/251 |
| work_keys_str_mv | AT kwekigrichipiifukorpcasagbaso highcaffeinecontainingenergydrinkinducedmetabolicstressinrats |