CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants

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Main Authors: Thaysa Leite Tagliaferri, Alex Krüttgen, Tiago Antônio de Oliveira Mendes, Simone Gonçalves dos Santos, Hans-Peter Horz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342280/?tool=EBI
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author Thaysa Leite Tagliaferri
Alex Krüttgen
Tiago Antônio de Oliveira Mendes
Simone Gonçalves dos Santos
Hans-Peter Horz
author_facet Thaysa Leite Tagliaferri
Alex Krüttgen
Tiago Antônio de Oliveira Mendes
Simone Gonçalves dos Santos
Hans-Peter Horz
author_sort Thaysa Leite Tagliaferri
collection DOAJ
format Article
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institution DOAJ
issn 1932-6203
language English
publishDate 2025-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-edbcf5cf3bad43d0a26cb7b7e11a51832025-08-20T03:06:48ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01208CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinantsThaysa Leite TagliaferriAlex KrüttgenTiago Antônio de Oliveira MendesSimone Gonçalves dos SantosHans-Peter Horzhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342280/?tool=EBI
spellingShingle Thaysa Leite Tagliaferri
Alex Krüttgen
Tiago Antônio de Oliveira Mendes
Simone Gonçalves dos Santos
Hans-Peter Horz
CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
PLoS ONE
title CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
title_full CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
title_fullStr CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
title_full_unstemmed CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
title_short CRISPR-Cas9 targeting the blaKPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
title_sort crispr cas9 targeting the blakpc gene in a clinical isolate of klebsiella michiganensis reduction of imipenem resistance and changes in genomic carbapenem resistance determinants
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342280/?tool=EBI
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