Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021
PURPOSEThis study used the latest data of Global Burden of Disease (GBD) 2021 to comprehensively analyze the burden of breast cancer among older adults (age >65 years) in Asian countries.METHODSOur focus was on breast cancer metrics in Asia, specifically incidence, prevalence, deaths, and disabil...
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American Society of Clinical Oncology
2025-06-01
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| Series: | JCO Global Oncology |
| Online Access: | https://ascopubs.org/doi/10.1200/GO-24-00523 |
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| author | Min Zhang Chao Ye Jing Qiu Min Zhao Meimei Cui Jiayi Chen Jingjing Jia Wenjie Yan Liling Zhu Limei Luo |
| author_facet | Min Zhang Chao Ye Jing Qiu Min Zhao Meimei Cui Jiayi Chen Jingjing Jia Wenjie Yan Liling Zhu Limei Luo |
| author_sort | Min Zhang |
| collection | DOAJ |
| description | PURPOSEThis study used the latest data of Global Burden of Disease (GBD) 2021 to comprehensively analyze the burden of breast cancer among older adults (age >65 years) in Asian countries.METHODSOur focus was on breast cancer metrics in Asia, specifically incidence, prevalence, deaths, and disability-adjusted life years (DALYs) using GBD 2021. Estimated annual percentage changes (EAPCs) were used to quantify the trends of age-standardized rates (ASRs). The decomposition method was explored to examine breast cancer deaths and DALYs as the result of four determinant factors. Nordpred was used to forecast burden trends up to 2044.RESULTSThere were 262,063.05 new cases, 2,742,285.75 prevalence, 115,973.98 deaths, and 2,260,975.34 DALYs of breast cancer among older adults in 2021 in Asia. From 1990 to 2021, the ASRs of breast cancer among older adults were on the rise. Males (EAPC, 4.14; 95% CI, 3.8 to 4.48) had a greater upward trend in age-standardized incident rate than females (EAPC, 2.09; 95% CI, 2.03 to 2.15). The regions and countries with the most significant ASR growth trends of all metrics were high-income Asia-Pacific and Türkiye, respectively. Decomposition analysis of the deaths and DALYs showed population growth was the primary contributing factor. By 2044, the estimated number of breast cancer cases among older adults will continue to increase in Asian countries.CONCLUSIONBreast cancer among older adults causes a high disease burden in Asia, especially in high-income Asia-Pacific. There is an urgent need for regional cooperation to take effective targeted measures to jointly prevent and control the spread of breast cancer among older adults, especially for male breast cancer. |
| format | Article |
| id | doaj-art-edbb063b98d44583bf4588c0b390ca77 |
| institution | Kabale University |
| issn | 2687-8941 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | American Society of Clinical Oncology |
| record_format | Article |
| series | JCO Global Oncology |
| spelling | doaj-art-edbb063b98d44583bf4588c0b390ca772025-08-20T03:46:20ZengAmerican Society of Clinical OncologyJCO Global Oncology2687-89412025-06-011110.1200/GO-24-00523Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021Min Zhang0Chao Ye1Jing Qiu2Min Zhao3Meimei Cui4Jiayi Chen5Jingjing Jia6Wenjie Yan7Liling Zhu8Limei Luo9Maternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaDepartment of Medical, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaDepartment of Ultrasound, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaDepartment of Immunoprevention and Administration, Shandong Center for Disease Control and Prevention, Jinan, ChinaMaternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaMaternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaMaternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaMaternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaSchool of Public Health, Jiamusi University, Jiamusi, ChinaMaternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, ChinaPURPOSEThis study used the latest data of Global Burden of Disease (GBD) 2021 to comprehensively analyze the burden of breast cancer among older adults (age >65 years) in Asian countries.METHODSOur focus was on breast cancer metrics in Asia, specifically incidence, prevalence, deaths, and disability-adjusted life years (DALYs) using GBD 2021. Estimated annual percentage changes (EAPCs) were used to quantify the trends of age-standardized rates (ASRs). The decomposition method was explored to examine breast cancer deaths and DALYs as the result of four determinant factors. Nordpred was used to forecast burden trends up to 2044.RESULTSThere were 262,063.05 new cases, 2,742,285.75 prevalence, 115,973.98 deaths, and 2,260,975.34 DALYs of breast cancer among older adults in 2021 in Asia. From 1990 to 2021, the ASRs of breast cancer among older adults were on the rise. Males (EAPC, 4.14; 95% CI, 3.8 to 4.48) had a greater upward trend in age-standardized incident rate than females (EAPC, 2.09; 95% CI, 2.03 to 2.15). The regions and countries with the most significant ASR growth trends of all metrics were high-income Asia-Pacific and Türkiye, respectively. Decomposition analysis of the deaths and DALYs showed population growth was the primary contributing factor. By 2044, the estimated number of breast cancer cases among older adults will continue to increase in Asian countries.CONCLUSIONBreast cancer among older adults causes a high disease burden in Asia, especially in high-income Asia-Pacific. There is an urgent need for regional cooperation to take effective targeted measures to jointly prevent and control the spread of breast cancer among older adults, especially for male breast cancer.https://ascopubs.org/doi/10.1200/GO-24-00523 |
| spellingShingle | Min Zhang Chao Ye Jing Qiu Min Zhao Meimei Cui Jiayi Chen Jingjing Jia Wenjie Yan Liling Zhu Limei Luo Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 JCO Global Oncology |
| title | Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 |
| title_full | Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 |
| title_fullStr | Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 |
| title_full_unstemmed | Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 |
| title_short | Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 |
| title_sort | burden of breast cancer disease among older adults in asian countries from 1990 to 2021 |
| url | https://ascopubs.org/doi/10.1200/GO-24-00523 |
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