Trans-omics analyses identify the biochemical network of LPCAT1 associated with coronary artery disease

Trans-omics analyses identify the biochemical network of LPCAT1 associated with coronary artery disease

Abstract Background Coronary artery disease (CAD) remains a leading cause of mortality in developed nations. While previous genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) linked to CAD, their impact on disease progression requires trans-omics validation. Metho...

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Main Authors: Paul Wei-Che Hsu, Chi-Hsiao Yeh, Chi-Jen Lo, Tsung-Hsien Tsai, Yun-Hsuan Chan, Yi-Ju Chou, Ning-I Yang, Mei-Ling Cheng, Wayne Huey-Herng Sheu, Chi-Chun Lai, Huey-Kang Sytwu, Ting-Fen Tsai
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Biomarker Research
Subjects:
Coronary artery disease (CAD)
LPCAT1
Single-nucleotide polymorphism (SNP)
Metabolomics
Machine learning
Biomarker
Online Access:https://doi.org/10.1186/s40364-025-00821-y
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