Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage

Nonlinear micro finite element (µFE) models have become the gold-standard for accurate numerical modeling of bone-screw systems. However, the detailed representation of bone microstructure, along with the inclusion of nonlinear material and contact, and pre-damage due to pre-drilling and screw-inser...

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Main Authors: Pia Stefanek, J. D. Silva-Henao, Victoria Fiedler, A. G. Reisinger, Dieter H. Pahr, Alexander Synek
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1524235/full
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author Pia Stefanek
J. D. Silva-Henao
J. D. Silva-Henao
Victoria Fiedler
A. G. Reisinger
A. G. Reisinger
Dieter H. Pahr
Alexander Synek
author_facet Pia Stefanek
J. D. Silva-Henao
J. D. Silva-Henao
Victoria Fiedler
A. G. Reisinger
A. G. Reisinger
Dieter H. Pahr
Alexander Synek
author_sort Pia Stefanek
collection DOAJ
description Nonlinear micro finite element (µFE) models have become the gold-standard for accurate numerical modeling of bone-screw systems. However, the detailed representation of bone microstructure, along with the inclusion of nonlinear material and contact, and pre-damage due to pre-drilling and screw-insertion, constitute significant computational demands and restrict model sizes. The goal of this study was to evaluate the agreement of screw pull-out predictions of computationally efficient, materially nonlinear µFE models with experimental measurements, taking both contact interface and pre-damage into account in a simplified way. Screw pull-out force was experimentally measured in ten porcine radius biopsies, and specimen-specific, voxel-based µFE models were created mimicking the experimental setup. µFE models with three levels of modeling details were compared: Fully bonded interface without pre-damage (FB), simplified contact interface without pre-damage (TED-M), and simplified contact interface with pre-damage (TED-M + P). In the TED-M + P models, the influence of pre-damage parameters (damage zone radial thickness and amount of damage) was assessed and optimal parameters were identified. The results revealed that pre-damage parameters highly impact the pull-out force predictions, and that the optimal parameters are ambiguous and dependent on the chosen bone material properties. Although all µFE models demonstrated high correlations with experimental data (R2 > 0.85), they differed in their 1:1 correspondence. The FB and TED-M models overestimated maximum force predictions (mean absolute percentage error (MAPE) > 52%), while the TED-M + P model with optimized pre-damage parameters improved the predictions (MAPE <17%). In conclusion, screw pull-out forces predicted with computationally efficient, materially nonlinear µFE models showed strong correlations with experimental measurements. To achieve quantitatively accurate results, precise coordination of contact modeling, pre-damage representation, and material properties is essential.
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spelling doaj-art-ed9a2e1af46943efa9ae7e098d7e96d22025-08-20T03:40:00ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-03-011310.3389/fbioe.2025.15242351524235Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damagePia Stefanek0J. D. Silva-Henao1J. D. Silva-Henao2Victoria Fiedler3A. G. Reisinger4A. G. Reisinger5Dieter H. Pahr6Alexander Synek7Institute of Lightweight Design and Structural Biomechanics, TU Wien, Vienna, AustriaInstitute of Lightweight Design and Structural Biomechanics, TU Wien, Vienna, AustriaDivision Biomechanics, Karl Landsteiner University of Health Sciences, Krems, AustriaDivision Biomechanics, Karl Landsteiner University of Health Sciences, Krems, AustriaInstitute of Lightweight Design and Structural Biomechanics, TU Wien, Vienna, AustriaDivision Biomechanics, Karl Landsteiner University of Health Sciences, Krems, AustriaInstitute of Lightweight Design and Structural Biomechanics, TU Wien, Vienna, AustriaInstitute of Lightweight Design and Structural Biomechanics, TU Wien, Vienna, AustriaNonlinear micro finite element (µFE) models have become the gold-standard for accurate numerical modeling of bone-screw systems. However, the detailed representation of bone microstructure, along with the inclusion of nonlinear material and contact, and pre-damage due to pre-drilling and screw-insertion, constitute significant computational demands and restrict model sizes. The goal of this study was to evaluate the agreement of screw pull-out predictions of computationally efficient, materially nonlinear µFE models with experimental measurements, taking both contact interface and pre-damage into account in a simplified way. Screw pull-out force was experimentally measured in ten porcine radius biopsies, and specimen-specific, voxel-based µFE models were created mimicking the experimental setup. µFE models with three levels of modeling details were compared: Fully bonded interface without pre-damage (FB), simplified contact interface without pre-damage (TED-M), and simplified contact interface with pre-damage (TED-M + P). In the TED-M + P models, the influence of pre-damage parameters (damage zone radial thickness and amount of damage) was assessed and optimal parameters were identified. The results revealed that pre-damage parameters highly impact the pull-out force predictions, and that the optimal parameters are ambiguous and dependent on the chosen bone material properties. Although all µFE models demonstrated high correlations with experimental data (R2 > 0.85), they differed in their 1:1 correspondence. The FB and TED-M models overestimated maximum force predictions (mean absolute percentage error (MAPE) > 52%), while the TED-M + P model with optimized pre-damage parameters improved the predictions (MAPE <17%). In conclusion, screw pull-out forces predicted with computationally efficient, materially nonlinear µFE models showed strong correlations with experimental measurements. To achieve quantitatively accurate results, precise coordination of contact modeling, pre-damage representation, and material properties is essential.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1524235/fullmicro finite element modelingbone-screw systemsbone-screw contactpredamage due to screw insertionefficient materially-nonlinear simulations
spellingShingle Pia Stefanek
J. D. Silva-Henao
J. D. Silva-Henao
Victoria Fiedler
A. G. Reisinger
A. G. Reisinger
Dieter H. Pahr
Alexander Synek
Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage
Frontiers in Bioengineering and Biotechnology
micro finite element modeling
bone-screw systems
bone-screw contact
predamage due to screw insertion
efficient materially-nonlinear simulations
title Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage
title_full Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage
title_fullStr Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage
title_full_unstemmed Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage
title_short Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage
title_sort screw pull out force predictions in porcine radii using efficient nonlinear µfe models including contact and pre damage
topic micro finite element modeling
bone-screw systems
bone-screw contact
predamage due to screw insertion
efficient materially-nonlinear simulations
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1524235/full
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